[HTML][HTML] Epidemic history and baseline resistance to NS5A-specific direct acting drugs of hepatitis C virus in Spain

C Palladino, IJ Ezeonwumelu, I Mate-Cano… - Scientific reports, 2020 - nature.com
… , the prevalence of NS5A resistance-associated substitutions (… among patients infected with
HCV genotype 1a in Spain, (A) … nationwide cross-sectional surveys of NS5A RASs to elbasvir

[HTML][HTML] Molecular Epidemiology and Baseline Resistance of Hepatitis C Virus to Direct Acting Antivirals in Croatia

P Simicic, A Slovic, L Radmanic, A Vince… - Pathogens, 2022 - mdpi.com
… RAS is advised before treatment with grazoprevir/elbasvir in patients … , this study analysed
the prevalence of resistance associated … This cross-sectional retrospective study included 300 …

[PDF][PDF] Molecular Epidemiology and Baseline Resistance of Hepatitis C Virus to Direct Acting Antivirals in Croatia. Pathogens 2022, 11, 808

P Simicic, A Slovic, L Radmanic, A Vince… - 2022 - repozitorij.mef.unizg.hr
… RAS is advised before treatment with grazoprevir/elbasvir in … this study analysed the prevalence
of resistance associated substi… Study Population This cross-sectional retrospective study

Prevalence of Naturally Occurring Resistance Associated Substitutions in NS3/4AProtease Inhibitors in Iranian HCV/HIV Infected Patients

K Baesi, AA Velayati, MF Ashtiani… - … HIV Research, 2021 - ingentaconnect.com
… , NS5A and NS5B, play crucial roles in the processing of viral … In this cross-sectional study,
blood samples were collected from … elbasvir (MK-8742) with or without ribavirin for hepatitis C

Direct Antiviral Agents for Hepatitis C

IW Fong - New Antimicrobials: For the Present and the Future, 2023 - Springer
… in the US in 2014, used to treat genotypes 1, 4, 5, and 6. … Elbasvir (EBR) is an NS5A inhibitor
and grazoprevir (GZR) is … patients in Spain, resistance-associated substitutions to EBR …

[HTML][HTML] Direct-acting antiviral regimens for patients with chronic infection of hepatitis C virus genotype 3 in China

X Wang, L Wei - Journal of Clinical and Translational Hepatology, 2021 - ncbi.nlm.nih.gov
… +L31M double NS5A resistance-associated substitutions. Phase … A Spanish randomized,
open-label trial reported that 12 … cross-sectional study in Beijing showed that the prevalence of …

Elbasvir and grazoprevir for the treatment of hepatitis C

SJ Wang, CF Huang, ML Yu - Expert review of anti-infective …, 2021 - Taylor & Francis
… a higher barrier to resistance-associated substitutions. Based … with no significant NS5A
RAS or low viral load [Citation36]. … infection and resulted in a low incidence of AEs [Citation24]. …

[PDF][PDF] Effectiveness and safety of elbasvir/grazoprevir therapy in patients with chronic HCV infection: Results from the Spanish HEPA-C real-world cohort

JV Hepat - academia.edu
… The presence of NS5A resistance- associated substitutions (… , elbasvir, and ribavirin for
chronic hepatitis C virus genotype … variants in genotype 1 patients across different regions using …

Discovery and development of antiviral therapies for chronic hepatitis C virus infection

MA Martinez, S Franco - Antiviral Drug Discovery and Development, 2021 - Springer
… to develop drug resistance-associated substitutions (RASs) … (VEL; NS5A inhibitor),
elbasvir (NS5A inhibitor) plus … for RASs among genotypes 1–4 (but not for genotypes 5 and …

Hepatitis C Guidance 2023 Update: AASLD-IDSA recommendations for testing, managing, and treating hepatitis C virus infection

D Bhattacharya, A Aronsohn, J Price… - Clinical Infectious …, 2023 - academic.oup.com
… Initial treatment using elbasvir/grazoprevir for genotype 1a … nonstructural protein 5A; RAS,
resistance-associated substitution… Recent cross-sectional surveys suggest that the HCV …