… NHEJ, which can generally be considered to involve three … , and DNA Ligase IV, we identified
a dimeric form of DNA-PK … a single copy of XLF was sufficient to repair DSBs studied.In …

… LigIV gene polymorphisms mainly hamper the efficient NHEJ … 5), we find that DBDWt and
all the three hypomorphic mutants … be sufficient to disturb the critical interactions necessary for …

… , including the amounts of ligase and the reaction cycles, the assembly efficiency of 4, 7, and
10 … all three enzymes (Figure 2B). Taking into account the lower price of T4 DNA ligase from …

… three core genes in the NHEJ pathway: ku80, DNA ligase IV (… mutation effects of NHEJ factors
on HDR due to low homing-… suppress c-NHEJ while it should be sufficient to compete with …

… and DNA ligase 4, inhibits NHEJ repair to the same degree. The … (4 h or less) inhibition
of ATM expression was sufficient to … of timosaponin A III (TAIII), which causes DNA damage, …

… effectively replaces a DNA repair protein for efficient NHEJ … of 0.5, 1, 2 and 4 s on three
sample concentrations (1, 2 and 5 … experiments carried out with T4 DNA ligase with a cycle of ∼…

… of the NHEJ system, including DNA Ligase IV, DNA-PKcs, … across three core components
of NHEJ, Ku70/80, DNA-PKcs … variants to nucleic acids due to a need for more sufficient data…

… , the DNA Ligase IV/XRCC4/XLF complex is recruited to DNA … that mtDNA damage is sufficient
to induce apoptosis or … processing NHEJ proteins such as Ku70/80, DNA-PKcs, Ligase IV/…

… /sgRNA sufficiently cuts target genes to produce DNA double-… LB plates (Figure 4A), and
the transformation rate was 3.3 × … via HR and T4 DNA ligase via NHEJ. These results showed …

… in single strand breaks repair induced by lowdose of UV. … We also show that depletion
of LIG1 is by itself sufficient for the … of the NHEJ complex, including Artemis, DNA Ligase IV, …