Dopamine-Loaded Polymer-Drug Conjugates for Potential Synergistic Anti-Cancer Treatment

T Naki, W Matshe, P Ubanako… - Polymer-Plastics …, 2022 - Taylor & Francis
… and doxorubicin for synergistic treatment. The prepared … of low molecular weight It limits the
uptake of the conjugates to the … to enhance the anticancer activity of the anticancer drugs with …

Polymer-drug conjugate, a potential therapeutic to combat breast and lung cancer

S Alven, X Nqoro, B Buyana, BA Aderibigbe - Pharmaceutics, 2020 - mdpi.com
… with a high molecular weight to low molecular weight products … and doxorubicin, resulting
in synergistic anticancer activity, … dual combination therapy using polymer-drug conjugates

Self-targeted polymersomal co-formulation of doxorubicin, camptothecin and FOXM1 aptamer for efficient treatment of non-small cell lung cancer

M Shahriari, SM Taghdisi, K Abnous… - Journal of Controlled …, 2021 - Elsevier
… the growth of tumor synergistically. Polymer-drug conjugates based on hyaluronic acid were
… of aptamers over monoclonal antibodies include low molecular weight, long storage period, …

HPMA-based polymeric conjugates in anticancer therapeutics

S Rani, U Gupta - Drug discovery today, 2020 - Elsevier
Polymerdrug conjugate based delivery is a technique in … While, another drug of low-molecular-weight
(LMW) can be … (PDT) in combination with adriamycin against neuroblastoma …

Polysaccharide-drug conjugates: A tool for enhanced cancer therapy

N Yadav, AP Francis, VV Priya, S Patil, S Mustaq… - Polymers, 2022 - mdpi.com
… starch doxorubicin (HES-SS-DOX) conjugate developed for … Chitosan with low molecular
weight suppresses the growth … as a drug carrier, can induce synergistic effects. The cytotoxic …

A Review on Exploring the Opportunities of Polymer Drug Conjugated Systems for Targeted Cancer Treatment

C Gupta, I Naik, M Menon, P Ambre… - Current Drug …, 2023 - ingentaconnect.com
… The low molecular weight drug molecules distribute rapidly in … , the conjugate showed superior
antitumor activity compared … age of the covalent conjugation of doxorubicin with chitosan (…

Polymer nanomedicines

J Kopeček, J Yang - Advanced drug delivery reviews, 2020 - Elsevier
… of water-soluble macromolecules with low molecular weight drugs and selected proteins. …
a) Combination chemotherapy of backbone degradable polymer-drug conjugates with immune …

Polymeric nanoparticle delivery of combination therapy with synergistic effects in ovarian cancer

SL Levit, C Tang - Nanomaterials, 2021 - mdpi.com
… including doxorubicin (topoisomerase inhibitor), camptothecin (… Curcumin, a low-molecular
weight polyphenol extracted from … that the polymer/drug combination increases apoptosis in …

Polymerdrug conjugation using ester and ortho-ester bond: Mechanism, protocols, and applications

M Chaudhary, R Tushir, N Chopra - Polymer-Drug Conjugates, 2023 - Elsevier
… It also reported the utility of low molecular weight polymer … antitumor candidate for combination
therapy with doxorubicin. … The synergistic effect produced by the combination therapy …

Drug–polymer conjugate tailoring by disulfide linkage for controlled and targeted drug delivery

S Thakur, R Sharma, S Sharma, A Mittal… - … -Drug Conjugates, 2023 - Elsevier
… , increase the solubility of low molecular weight medicines, and … , doxorubicin, and gemcitabine
Hyaluronic acid Combination … and DOX that had synergistic anticancer activity. It was …