Morphometry: stereological theory and practical methods

ER Weibel - Models of lung disease, 2020 - taylorfrancis.com
… question that is commonly asked is about the number of alveoli making up the lung. Not …
in attempts to find a morphometric basis for lung function. To find the morphometric variables of …

Stereology as the 3D tool to quantitate lung architecture

L Knudsen, C Brandenberger, M Ochs - Histochemistry and Cell Biology, 2021 - Springer
structural features in the lung in a more comprehensive way than the classical physical
disector approach. In this regard, three-dimensional datasets in which the investigators can scroll …

Development of human respiratory airway models: A review

K Ahookhosh, O Pourmehran, H Aminfar… - European Journal of …, 2020 - Elsevier
… Drug delivery into the respiratory system is influenced by many anatomical … lung morphometry,
breathing patterns, fluid dynamics, particle properties, etc. The respiratory airway structure

Is computed tomography airway count related to asthma severity and airway structure and function?

RL Eddy, S Svenningsen, M Kirby… - … Journal of Respiratory …, 2020 - atsjournals.org
… uniquely explained airway wall morphology (WA%), … relationship between CT or MRI lung
volume and airway count, and the fact that most studies acquire CT close to TLC (16). CT lung

Localization of macrophages in the human lung via design-based stereology

PS Hume, SL Gibbings, CV Jakubzick… - … journal of respiratory …, 2020 - atsjournals.org
… The distribution of AMs between the conducting airway lumens and the gas-exchanging
airspaces has not been previously described. Thus, although our morphometry protocol was …

Quantitative CT analysis of diffuse lung disease

A Chen, RA Karwoski, DS Gierada, BJ Bartholmai… - Radiographics, 2020 - pubs.rsna.org
… in lower lung density, such as emphysema. However, threshold-based measures that do
not assess morphology or local spatial relationships cannot differentiate between different …

[HTML][HTML] Pathology of idiopathic pulmonary fibrosis assessed by a combination of microcomputed tomography, histology, and immunohistochemistry

N Tanabe, JE McDonough, DM Vasilescu… - The American journal of …, 2020 - Elsevier
… tested the direct relationship between the pathological UIP and IPF criteria and morphometric
assessment of lungs with IPF. Therefore, the close correlations between alveolar surface …

[HTML][HTML] Structural hallmarks of lung surfactant: Lipid-protein interactions, membrane structure and future challenges

JC Castillo-Sánchez, A Cruz, J Pérez-Gil - … of biochemistry and biophysics, 2021 - Elsevier
lung. The present review dissects the complexity of the structure-function relationships in LS
… lipid-protein interactions and the membrane structures that sustain its synthesis, secretion, …

Effects of lumacaftor–ivacaftor on lung clearance index, magnetic resonance imaging, and airway microbiome in Phe508del homozygous patients with cystic fibrosis

SY Graeber, S Boutin, MO Wielpütz… - Annals of the …, 2021 - atsjournals.org
… improved changes in lung morphology and perfusion detected by … into the relationship
between the degree of functional correction … and adult patients with CF and chronic lung disease. …

Low-dose CT–derived bronchial parameters in individuals with healthy lungs

I Dudurych, GJ Pelgrim, G Sidorenkov, A Garcia-Uceda… - Radiology, 2024 - pubs.rsna.org
lungs, participants with self-reported history of pulmonary disease, medication use for respiratory
… parameters in individuals with normal lung function, we measured the airways of 8869 …