Stress relief techniques: p38 MAPK determines the balance of cell cycle and apoptosis pathways
RH Whitaker, JG Cook - Biomolecules, 2021 - mdpi.com
… activated protein kinases (MAPKs) are components of kinase … signaling pathways and
cell regulatory mechanisms, in this review we focus on the roles that the p38 stress pathway …
cell regulatory mechanisms, in this review we focus on the roles that the p38 stress pathway …
p38 MAPK pathway in the heart: new insights in health and disease
R Romero-Becerra, AM Santamans… - International Journal of …, 2020 - mdpi.com
… shown to decrease oxidative stress and block the activation of p38 and JNK, thus reducing
apoptosis during ischemia–reperfusion [68]. Moreover, oxidative stress can directly regulate …
apoptosis during ischemia–reperfusion [68]. Moreover, oxidative stress can directly regulate …
Understanding MAPK signaling pathways in apoptosis
J Yue, JM López - International journal of molecular sciences, 2020 - mdpi.com
… /threonine kinase, which was termed MAP kinase (MAPK) as … The stress-activated JNKs and
p38 MAPKs play key roles in … to both extracellular and intracellular stresses (reviewed in [12…
p38 MAPKs play key roles in … to both extracellular and intracellular stresses (reviewed in [12…
Involvement of p38 MAPK in synaptic function and dysfunction
C Falcicchia, F Tozzi, O Arancio, DM Watterson… - International journal of …, 2020 - mdpi.com
… Each isoform of the p38 MAPK enzyme is activated by dual … by either MAP kinase kinase 3
(MKK3) or MAP kinase kinase 6 … , the differential activation of stress related kinases, p38mapk, …
(MKK3) or MAP kinase kinase 6 … , the differential activation of stress related kinases, p38mapk, …
Is p38 MAPK associated to drugs of abuse-induced abnormal behaviors?
R El Rawas, IM Amaral, A Hofer - International Journal of Molecular …, 2020 - mdpi.com
… of the mitogen-activated protein kinases (MAPK) mediate a wide … of p38 MAPK in stress,
anxiety, and depression. We opine that p38 MAPK activation is more closely associated to stress-…
anxiety, and depression. We opine that p38 MAPK activation is more closely associated to stress-…
Functions of p38 MAP kinases in the central nervous system
… of p38 activation are cellular stressors such as oxidative stress, … Upstream stimuli activate a
MAP kinase kinase kinase (… MLK or TAO kinases, which in turn phosphorylate and activate a …
MAP kinase kinase kinase (… MLK or TAO kinases, which in turn phosphorylate and activate a …
Diversity and versatility of p38 kinase signalling in health and disease
B Canovas, AR Nebreda - Nature reviews Molecular cell biology, 2021 - nature.com
… of the mitogen-activated protein kinase (MAPK) … of p38 kinase signalling compared with
stress and cytokines 66,67 . We discuss below examples of pathways involved in p38α activation …
stress and cytokines 66,67 . We discuss below examples of pathways involved in p38α activation …
Impact of environmental toxicants on p38-and ERK-MAPK signaling pathways in the central nervous system
… -activated protein kinases (MAPKs) signalling pathways, which include the extracellular
signal-regulated protein kinase (ERK) and the p38-MAPK, … and oxidative stress by disrupting the …
signal-regulated protein kinase (ERK) and the p38-MAPK, … and oxidative stress by disrupting the …
The p38 pathway: from biology to cancer therapy
A Martínez-Limón, M Joaquin, M Caballero… - International journal of …, 2020 - mdpi.com
… The p38 MAPK pathway is well known for its role in transducing stress signals from the …
Mitogen-activated protein kinase (MAPK) cascades are signaling components that show a high …
Mitogen-activated protein kinase (MAPK) cascades are signaling components that show a high …
The p38 MAPK signaling activation in colorectal cancer upon therapeutic treatments
A Pranteda, V Piastra, L Stramucci… - International Journal of …, 2020 - mdpi.com
… exact role of the p38 MAPK pathway in response to currently … intricate scenario in which the
p38 MAPK node presents many … stress-activated p38 mitogen activated protein kinase (MAPK…
p38 MAPK node presents many … stress-activated p38 mitogen activated protein kinase (MAPK…