[HTML][HTML] A review of current evidence about lncRNA MEG3: A tumor suppressor in multiple cancers

J Xu, X Wang, C Zhu, K Wang - Frontiers in cell and developmental …, 2022 - frontiersin.org
… the downregulation of MEG3 led to the osteoarthritis (OA) … degradation through the miR-361-5p/FOXO1
pathway in OA (… suppressor through the MEG3-miRNA-mRNA axis. In addition, …

Role of LncRNA in Rheumatoid Arthritis

A Kocak - Rheumatoid Arthritis, 2022 - books.google.com
… NF-kB axis have also been established in chondrocytes in RA… We can say that LncRNA
MEG3 promotes proliferation and it … (Lnc-IL7R) inhibits apoptosis and leads to proliferation [42]. …

[HTML][HTML] Dysregulation of lncRNAs in rheumatoid arthritis: biomarkers, pathogenesis and potential therapeutic targets

C Miao, L Bai, Y Yang, J Huang - Frontiers in pharmacology, 2021 - frontiersin.org
… The C/EBPβ/NTT/PBOV1 axis was overactivated in PBMCs of … In LPS-treated chondrocytes,
the cell proliferation rate and … inhibitor 5-azadc could inhibit the hypermethylation of MEG3

MiR-361-5p promotes oxygen–glucose deprivation/re-oxygenation induced neuronal injury by negatively regulating SQSTM1 in vitro

T Zeng, S Zhang, Y He, Z Liu, Q Cheng - Metabolic Brain Disease, 2021 - Springer
… , and miR-361-5p inhibition efficiently protected against apoptosis in neurons and reduced
I/… neuron injury in vitro and confirmed the regulatory axis between miR-361-5p and SQSTM1. …

ox-LDL regulates proliferation and apoptosis in VSMCs by controlling the miR-183-5p/FOXO1

M Fan, Y Huang, K Li, X Yang, J Bai, Q Si, Z Peng… - Genes & Genomics, 2022 - Springer
axis may be involved in imbalanced VSMC proliferation/… in cellular proliferation or that they
promote proliferation; thus, … reported to inhibit proliferation and promote apoptosis in various …

LncRNA nuclear receptor subfamily 2 group F member 1 antisense RNA 1 (NR2F1-AS1) aggravates nucleus pulposus cell apoptosis and extracellular matrix …

L Du, X Li, Q Gao, P Yuan, Y Sun, Y Chen… - …, 2022 - Taylor & Francis
… that MEG3 facilitates OA chondrocytesproliferation and … and ECM degradation through the
miR-361-5p/FOXO1 pathway… NR2F1-AS1 modulates the FOXO1 axis by sponging miR-145-…

[HTML][HTML] An evaluation of the role of miR-361-5p in senescence and systemic ageing

E Manni, N Jeffery, D Chambers, L Slade… - Experimental …, 2023 - Elsevier
… given on the Y axis and days from start of analysis is given on the X axis. Data from control
… elegans orthologues are given on the Y axis, and the identity of the gene on the X axis. Error …

[HTML][HTML] Emerging role of lncRNAs in osteoarthritis: An updated review

R Wang, HT Shiu, WYW Lee - Frontiers in immunology, 2022 - frontiersin.org
… and migration and inhibiting apoptosis (195). Zhang and … axis enhances proliferation of
chondrocyte in osteoarthritis. Acta … in osteoarthritis via regulating miR-373-3p/SOX4 axis. Eur Rev …

The Impact of Non-coding RNA Networks on Disease Comorbidity: Cardiometabolic Diseases, Inflammatory Diseases, and Cancer

P Holvoet, P Holvoet - Non-coding RNAs at the Cross-Road of …, 2021 - Springer
chondrocytes apoptosis and promoted cartilage remodeling in mice with osteoarthritis (OA)
[55]… De-repressing MEG3 in fibroblast-like synoviocytes of RA patients inhibited inflammation …

Research progress on the pathogenesis of knee osteoarthritis

X Du, Z Liu, X Tao, Y Mei, D Zhou, K Cheng… - Orthopaedic …, 2023 - Wiley Online Library
… of proliferation and apoptosis of chondrocytes in the … -3p axis to protect osteoarthritis. In
conclusion, lncRNA plays an important role in regulating gene expression, maintaining cartilage