Nfib promotes chondrocyte proliferation and inhibits differentiation by mildly regulating Sox9 and its downstream genes

D Pan, B Qian, D Zhao, B Yao - Molecular Biology Reports, 2021 - Springer
Meg3 is a maternally expressed imprinted gene that can act on osteoarthritis chondrocytes
by promoting cell proliferation, inhibiting cell apoptosis and ECM degradation [31]. Matn3 is …

The role of the long non-coding RNA MALAT1 in mediating inflammation in the human osteoarthritis joint

FAQ Alnajjar - 2022 - etheses.bham.ac.uk
… to inhibit apoptosis of OA chondrocytes via miR-145/SP1/NF-kB … However, MEG3 lncRNA
was shown to protect ECM … /ADAMTS-5 axes and articular chondrocytes apoptosis was shown …

Exosomal miRNA in the repair mechanism of degenerative diseases of the spine and joints

Y Zhao, Q Xia, S Xiang, Q Mao, W Kong… - Chinese Journal of …, 2023 - cjter.com
Meg3 promotes proliferation and inhibits apoptosis in osteoarthritis chondrocytes by mir-361-5p/foxo1
axis. … Upregulation of microrna-9-5p inhibits apoptosis of chondrocytes through …

LncRNA MEG3-TRPV1 signaling regulates chronic inflammatory pain in rats

JW Peng, YY Gu, J Wei, Y Sun, CL Zhu… - Molecular …, 2022 - journals.sagepub.com
Osteoarthritis (OA) is a … MEG3 is involved in articular cartilage inflammation and may be
a novel potential target for OA. A previous study showed that MEG3 lncRNA in the cartilage

Mutant MEG3 Enhances the Activity of Telomerase by Increasing DNA Damage Repair in Human Liver Cancer Stem Cells

S Song, S Xie, R Qin, Y Lu, L Wang, Y Chen, X Jiang… - 2021 - researchsquare.com
… Mechanistically, our results show that mutant MEG3 enhances acetylation … MEG3 promotes
proliferation and inhibits apoptosis in osteoarthritis chondrocytes by miR-361-5p/FOXO1 axis. …

Identification of Characteristic lncRNA Molecular Markers in Osteoarthritis by Integrating GEO Database and Machine Learning Strategies and Experimental Validation

Z Qiao, XIN Ling, F Yanyan, QI Yajun… - Journal of Sichuan …, 2023 - jsu-mse.com
… trees, with the vertical axis of error representing the error; the horizontal axis of trees
representing the tree … inhibits apoptosis in osteoarthritis chondrocytes by miR-361-5p/FOXO1

lncRNA Zeb1-AS1 调控JAK2/STAT3 信号通路影响骨关节炎软骨细胞的增殖和凋亡

刘旋, 张磊, 张凤军 - 蚌埠医学院学报, 2023 - xuebao.bbmc.edu.cn
… the proliferation and apoptosis of osteoarthritis chondrocytes … -AS1 can promote the proliferation
and inhibit apoptosis of … 母系表达基因3(MEG3)表达降低,过表达MEG3促进软骨细胞增殖…

[HTML][HTML] GEO 数据库联合机器学习策略识别骨关节炎特征性lncRNA 分子标志物及实验验证

巧周, 健刘, 凌忻, 妍妍方, 亚军齐… - Journal of Sichuan …, 2023 - ncbi.nlm.nih.gov
… 骨关节炎(osteoarthritis, OA)是慢性关节疼痛和残疾的主要原因之一 [1] 。OA早期诊断困难,…
, with the vertical axis of error representing the error; the horizontal axis of trees representing …

[PDF][PDF] 实验动物屏障设施微生物污染防控管理要点

张薇, 王牧孜, 邓少嫦 - 中国比较医学杂志, 2023 - zgbjyx.cnjournals.com
MEG3 promotes proliferation and inhibits apoptosis in osteoarthritis chondrocytes by miR-3615p/
FOXO1 axis [J]. BMC Med Genomics, 2019, 12(1): 201. [20] Lin JY, Kuo WW, Baskaran …