… of the MET/HGF axis in tumour progression and dissemination of pancreatic cancer. Therapeutic
… The HGF/c-MET pathway that mediates cross-talk between pancreatic stellate cells (the …

… (PD-L1) are currently the most popular weapon in cancer immunotherapy. PD-L1 binds to
PD-1 … Increasing evidence reveals that co-targeting these regulatory pathways with PD-L1 can …

… factors have been observed to play crucial roles in cancer cell … individual growth factors in
pancreatic cancer chemoresistance. … Furthermore, the crosstalk between the FGF10 and TGF-β …

… The TGF-β/Smad4 signaling axis plays an important role in regulating the TME and
mediating tumor-stroma crosstalk [84]. The Met/HGF pathway not only involves the interaction …

… In a study evaluating the prognostic importance of the blood HGF level, it was determined
that the blood HGF level in patients having pancreatic cancer was observed to have …

… Pancreatic cancer is predicted to be the second-highest cause of cancer mortality in the
US … Roughly 1 in 10 patients with pancreatic cancer have wildtype KRAS (KRAS WT ). We …

… Lentivirus knockdown was performed to investigate the impact of AHNAK2 on the biological
function of pancreatic cancer cells. The subcutaneous cell-derived xenograft (CDX) model …

… have reviewed the literature for circular RNAs (circRNAs) with efficacy in preclinical
pancreatic-cancer … potential new entities for treatment of pancreatic cancer. Up-regulated …

… cancer, among others 2 , 4 - 11 , and associated with an aggressive phenotype and poor
prognosis in pancreatic cancer … by TIMER, a web tool for researching infiltrated immune cells in …

… across 13 pancreatic ductal adenocarcinoma PDX models. This … In summary, we present
a comprehensive landscape of … therapeutic target in pancreatic ductal adenocarcinoma. …