… In this Review, we discuss examples of how macrophages develop in barrier and internal
organs and describe their roles in regulating homeostatic functions within these organs. We …

… macrophages (only macrophages are depicted here). EMP-derived macrophages develop
in the absence of MYB and persist in postnatal tissues as resident macrophages. Within the …

… These HSC-derived macrophages are a long-lived pool that will … tissue-resident macrophages,
their molecular regulation in specific tissues, and their impact on embryonic development …

… with a special focus on the intestinal tissue of each species when data are available. We
consider more precisely the local and regional specialization of MFs in the mammalian intestine …

… The tissue microenvironment is a major driver in imprinting tissue-specific macrophage
functions in various mammalian tissues. As monocytes are recruited into the gastrointestinal (GI) …

… during development and aging; (3) inflammation status; and (4) the cumulative effect of time
spent in a specific tissue that contributes to the resilient adaptation of macrophages to their …

… , macrophages residing in key metabolic organs such as the liver and adipose tissue, as well
as macrophages … complexity of tissue-macrophage functions and their regulation by tissue-…

… Activated macrophages develop different properties, such as the vigorous production of
inflammatory molecules such as tumor necrosis factor (TNF) and interleukins (ILs), clotting factors…

… that regulate the specialization of resident macrophages in many tissues [5]. Headway has
also been made in identifying the drivers that underlie specialization in certain tissues. For …

… those cells are macrophages, a … macrophages support tissue modules within glands via the
creation of mutually beneficial cell-cell circuits. A better comprehension of gland macrophage …