[HTML][HTML] Signature of long-lived memory CD8+ T cells in acute SARS-CoV-2 infection
… Here, using spectral flow cytometry combined with cellular … -Dex + cells longitudinally,
at both the population level and … for memory generation 34 . As we sampled SARS-CoV-2-specific …
at both the population level and … for memory generation 34 . As we sampled SARS-CoV-2-specific …
[HTML][HTML] Sepsis leads to lasting changes in phenotype and function of memory CD8 T cells
… Here, using samples from septic patients and well described … LCMV-infection model to
establish memory CD8 T cells followed … This system of memory generation and sepsis induction …
establish memory CD8 T cells followed … This system of memory generation and sepsis induction …
Peripherally induced brain tissue–resident memory CD8+ T cells mediate protection against CNS infection
… , we compared CNS T RM cell generation in mice infected in with … The percentage of IV –
antigen-specific cells in the upper … TCR-tg T cell populations were gated using FlowJo software …
antigen-specific cells in the upper … TCR-tg T cell populations were gated using FlowJo software …
CD8+ T cell metabolism in infection and cancer
M Reina-Campos, NE Scharping… - Nature Reviews …, 2021 - nature.com
… killing of infected cells, while long-lived memory CD8 + T cell … using this in vitro system
suggested that memory CD8 + T … to couple oxidative phosphorylation with the generation of ATP …
suggested that memory CD8 + T … to couple oxidative phosphorylation with the generation of ATP …
Tissue-resident memory CD8+ T cells shape local and systemic secondary T cell responses
FM Behr, L Parga-Vidal, NAM Kragten… - Nature …, 2020 - nature.com
… specifically visualize and manipulate T RM cells. Therefore, … Hobit-expressing OT-I T cells
after primary infection (Fig. 2a). … Mapping and generation of count tables were done using the …
after primary infection (Fig. 2a). … Mapping and generation of count tables were done using the …
The architectural design of CD8+ T cell responses in acute and chronic infection: Parallel structures with divergent fates
… goal of generating large numbers of effector T cells to help … Comparative analyses of the
effector and memory CD8 + T cell … As the determination of cell subsets or states using single-cell …
effector and memory CD8 + T cell … As the determination of cell subsets or states using single-cell …
[HTML][HTML] Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection
… of IFNγ + T cells ± SEM; Percentage shown on top of the … may have led to the generation
of T cell immunity even in the … contacts and 30 healthy donors by using an overnight “ex vivo” …
of T cell immunity even in the … contacts and 30 healthy donors by using an overnight “ex vivo” …
[HTML][HTML] Diverse CD8 T cell responses to viral infection revealed by the collaborative cross
MD Martin, R Sompallae, CS Winborn, JT Harty… - Cell reports, 2020 - cell.com
… factors influencing memory CD8 T cell generation and characteristics of … CD8 T cells dictate
the level of host protection against re-… memory CD8 T cells with time after primary infection. …
the level of host protection against re-… memory CD8 T cells with time after primary infection. …
Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection
… , we assessed CD8 T cell responses using multiplexed human … without preventing the
generation of de novo responses to … of pre-infection spike-specific memory CD8 T cells toward the …
generation of de novo responses to … of pre-infection spike-specific memory CD8 T cells toward the …
Differentiation of exhausted CD8+ T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory
…, L Massenet-Regad, T Eisenhaure… - Nature …, 2021 - nature.com
… of HCV-specific CD8 + T cells using HLA class I multimers … in each patient using next-generation
viral sequencing (Fig. … versus memory CD8 + T cell (C7)’ enriched in pre-DAA T EX cells …
viral sequencing (Fig. … versus memory CD8 + T cell (C7)’ enriched in pre-DAA T EX cells …