… and disulfide bond mapping in mAb. The results demonstrate that ProAlanase is highly suitable
for proteomics … is efficient in disulfide bond mapping, showing high coverage of disulfide-…

Disulfide bonds in proteins have a substantial impact on protein structure, stability, and biological
activity. Localizing disulfide bonds is … for disulfide-intact proteins, can access disulfide …

… detailed map of the folding pathway and the folding kinetics can be constructed (Scheme
2). … -containing proteins constitute approximately 15% of the human proteome [113,114]. …

… dissociation of the disulfide bonds, their application to mapping the noncovalent interactions
… -containing proteins account for about a third of the human proteome, (28) and their fraction …

… This investigation is focused on mapping the intra, and inter-chain disulfide bonds in the in …
two intra-chain disulfide bonds on each subunit and a single inter-chain disulfide linkage. rHu …

… disulfide bonds, we reported the disulfide bond data as the XIC sum contribution of all shuffled
disulfide bonds … of all (shuffled and expected) detected disulfide bonds. For the trisulfide …

… Further interrogation revealed the presence of two cysteine amino acids within Somatostatin-28,
and we hypothesise that a possible disulphide bond was causing a subtle mass shift …

… native disulfide bonds; ie, only native disulfide bonds provoke folding to form native-like/native …
Analytical limitations have prevented mapping the distribution of disulfide bonds in the 3S …

… not been fully explored at the whole-proteome level. We combined AlphaFold2-predicted
side-chain accessibilities for >95% of the human proteome with a meta-analysis of eighteen …

… the disulfide bridges present in the human milk proteome by a … relative quantification of the
disulfide bridges. Human milk from six … Mapping of disulfide bridges onto the protein structures …