Phenotypic mapping of pathologic cross-talk between glioblastoma and innate immune cells by synthetic genetic tracing

MJ Schmitt, C Company, Y Dramaretska, I Barozzi… - Cancer discovery, 2021 - AACR
glioblastoma, synthetic genetic tracing causally connects cellular and molecular heterogeneity
to therapeutic responses… IDH1 status in patients with high-grade glioma and are hereafter …

Effect of awake craniotomy in glioblastoma in eloquent areas (GLIOMAP): a propensity score-matched analysis of an international, multicentre, cohort study

JKW Gerritsen, RH Zwarthoed, JL Kilgallon… - The Lancet …, 2022 - thelancet.com
… Asleep or awake motor mapping for resection of perirolandic glioma in the nondominant
hemisphere? Development and validation of a multimodal score to tailor the surgical strategy. …

Genetic, cellular, and connectomic characterization of the brain regions commonly plagued by glioma

AS Mandal, R Romero-Garcia, MG Hart, J Suckling - Brain, 2020 - academic.oup.com
… We combined neuroimaging data from 335 adult patients with high- and low-grade glioma
to form a replicable tumour frequency map. Using this map, we demonstrated that glioma

Current FDA-approved therapies for high-grade malignant gliomas

JP Fisher, DC Adamson - Biomedicines, 2021 - mdpi.com
… and allows for intraoperative visualization of malignant glioma tissue via fluorescence-guided …
The new genomic era has made it possible to map individual patient glioma genomes and …

Visualization of diagnostic and therapeutic targets in glioma with molecular imaging

D Li, CB Patel, G Xu, A Iagaru, Z Zhu, L Zhang… - Frontiers in …, 2020 - frontiersin.org
treatment response to anti-glioma therapies. Additional details about the tracers routinely
utilized in glioma diagnosis and therapy … in glioma patients, and thus noninvasively map crucial …

Tumor treating fields in the management of patients with malignant gliomas

AP Ghiaseddin, D Shin, K Melnick, DD Tran - … treatment options in oncology, 2020 - Springer
… Thus, TTFields delivered according to NovoTAL mapping have both high targeting selectivity
… Since TTFields only exert a therapeutic effect when the device is actively utilized and, thus, …

Diffuse glioma heterogeneity and its therapeutic implications

JG Nicholson, HA Fine - Cancer discovery, 2021 - AACR
… harboring multiple genetically distinct subclones; (ii) epigenetic heterogeneity, with malignant
glioma cells mimicking developmental cellular hierarchies and occupying a diverse range …

[HTML][HTML] Single-cell mapping of human brain cancer reveals tumor-specific instruction of tissue-invading leukocytes

E Friebel, K Kapolou, S Unger, NG Núñez, S Utz… - Cell, 2020 - cell.com
… Here, we have mapped the leukocyte landscape of brain tumors using high-dimensional
single-… Only a selective group of patients with temozolomide-induced hypermutations in gliomas

Triple motor mapping: transcranial, bipolar, and monopolar mapping for supratentorial glioma resection adjacent to motor pathways

AJ Gogos, JS Young, RA Morshed, LN Avalos… - Journal of …, 2020 - thejns.org
… The authors reviewed their use of multiple techniques to map and monitor patients' motor
function during glioma surgery. They demonstrated that their method of triple motor mapping

[HTML][HTML] Immune infiltrating cells-derived risk signature based on large-scale analysis defines immune landscape and predicts immunotherapy responses in glioma …

N Zhang, H Zhang, Z Wang, Z Dai, X Zhang… - Frontiers in …, 2021 - frontiersin.org
… in glioma cells, tumor microenvironment (TME) also plays a critical role in tumor proliferation,
progression, and therapeutic responses … to count the reads numbers mapped to each gene. …