… in renal fibrosis remains controversial, partial EMT is an indispensable part of renal fibrosis
[… and progression of renal fibrosis by impairing the integrity of renal tubular epithelium and …

… UUO-induced renal fibrosis is known to show progression of renal fibrosis and experimental
… 7 inhibitor, compound 15, on renal fibrosis in a mouse model of UUO-induced renal fibrosis. …

… Chronic kidney disease (CKD) is characterized by the loss of kidney function. The
molecular mechanisms underlying the development and progression of CKD are still not fully …

… Our results extend reports on chronic kidney disease (27), demonstrating elevation of the
active form of MMP7 in urine samples from patients with MPO-AAV. We further confirmed that …

… The function of MMP-7 in kidney disease may differ for CKD and AKI; it may have a
profibrotic role in CKD and an anti-apoptotic and regenerative function in AKI. Additionally, the …

… rabbit kidneys and IR kidneys by RNA-sequencing, then identified that matrix metalloproteinase–7
(… Indeed, A time-dependent promotion of renal injury was detected in rabbit model, as …

… Thus, the identification of novel non-invasive renal fibrosis … biomarkers associated with
renal fibrosis evaluated in patients … complexity characterizing the renal fibrotic process, having …

… development of renal fibrosis, an important pathological process of chronic kidney disease
(… 1 (CUX1) has shown profound effects on several kidney diseases. However, its role in CKD …

… Those results are promising, and MMP-7 has been considered a predictive biomarker in
other fibrogenesis pathologies, such as kidney fibrosis and idiopathic pulmonary fibrosis[31,32]. …

… renal cancer was MMP-7: actually, its concentration surpassed the threshold level of 3 ng/ml
in 84% cases as early as stage I of the disease. … Matrix metalloproteinases 7 and 9 and their …