… MaveDB, a public, open source repository for multiplexed … MaveDB is designed to store and
distribute multiplexed … To enable the discovery, reuse, and interpretation of data in MaveDB, …

… Multiplexed assays of variant effect (MAVEs) are capable of experimentally testing all …
evidence to enable more rapid and accurate clinical interpretation of human variation. Because the …

… describe the biological and disease relevance of the assay. In addition to releasing scores
and … through MaveDB, an open-source platform to distribute and interpret MAVE data [15, 16]. …

… of ClinVar and MaveDB to enact software changes that … of pathogenicity would even be
distributed by contiguous linear … and/or in silico data, which could then be interpreted by the …

… Multiplexed assays of variant effect (MAVEs) can … have each contributed many variant
interpretations to ClinVar. The … when available, displaying the distribution of single-nucleotide …

… Multiplexed assays of variant effect (MAVEs) can generate … measured to the measurements
deposited into the MaveDB. … a human cell line assay and if the interpreter considered this to …

… on external software libraries beyond … distribution of abundances by sample, and static or
interactive MA plots and volcano plots for easier interpretation of the statistical analysis results. …

… Next-generation sequencing (NGS) improves upon platforms … Each variant's distribution
across the bins is converted into … of multiplexed functional data for clinical variant interpretation…

… TheraPy, our open-source drug normalization tool, performs … of multiplex assays of variant
effect (MAVE) data, but the assay… Our effort enables the dissemination of MaveDB data to down…

… found in clinical genetic testing are interpreted and also to … Multiplexed variant functional
data can also transform our … been developed, for example the MaveDB repository [45, 46], …