… In this direction, we generated a yeast strain expressing Myc epitope-tagged Mdm30 and
hemagglutinin (HA)-tagged Sub2 or Mex67 from their chromosomal loci and then performed an …

… mitochondria to the endoplasmic reticulum (ER), the yeast … of Fzo1 is regulated by Mdm30
and FA desaturation. Our data … TCA cycle thereby maintaining the mitochondrial membrane …

… regulation, circadian clock maintenance, mitochondrial connectivity, sexual reproduction, …
by F-box protein MDM30 without splicing or mitochondrial function. MDM30 an F-box protein …

… cerevisiae, F-box protein Mdm30 is involved in Fzo1 degradation and is required for mitochondrial
… Mdm30 homologs are found exclusively in the budding yeast clade, and no functional …

… , and aging, the maintenance of mitochondrial function is of … protein Ugo1 and the F-box
protein Mdm30 are required for … , the role of mitochondrial dynamics for mitophagy in yeast is not …

… The F-box protein, the CRL substrate recognition … yeast, F-box protein Mdm30 was shown
to target Fzo1 (an ortholog of mammalian mitofusion1/2) or Mdm34, two mitochondrial proteins …

… to mitochondria under stress, where it ubiquitylates the yeast … Consistently, deletion of MDM30
prevented Ufd2 from … -fermentable media or mtDNA maintenance in both Dfzo1 and Dfzo1…

… In conclusion, maintenance of the mitochondrial proteome is … ligases SCF Mdm30 and Parkin
were shown to ubiquitylate yeast, … is required for creating fusion-competent forms of Fzo1. …

… of mitochondrial proteins in the yeast Saccharomyces … for maintaining the protein in its
functional, fusion-competent … of mitochondrial fusion by the F-box protein Mdm30 involves …

… For example, the F-box protein Mdm30p is essential for … fusion to maintain fusion-competent
mitochondria in yeast, and … both proteins are essential for the maintenance of mitochondrial …