Molecular identification of spatially distinct anabolic responses to mechanical loading in murine cortical bone
… signal (1 dot or less per 10 cells, RNAscope guidelines). Visualization of positive control probes
for (1) Gapdh, a commonly used control … related mechanically and both undergo exercise…
for (1) Gapdh, a commonly used control … related mechanically and both undergo exercise…
Extracellular-matrix mechanics regulate cellular metabolism: a ninja warrior behind mechano-chemo signaling crosstalk
X Liao, X Li, R Liu - Reviews in Endocrine and Metabolic Disorders, 2023 - Springer
… is sensed by cells and signals to modulate diverse cell metabolic … the cue of mechanical
forces to adjust the activity of other … to a metabolic switch shifting to anabolism, thereby inhibiting …
forces to adjust the activity of other … to a metabolic switch shifting to anabolism, thereby inhibiting …
How the mechanical microenvironment of stem cell growth affects their differentiation: A review
X Zhang, S Zhang, T Wang - Stem cell research & therapy, 2022 - Springer
… or the activity of associated intracellular receptors, transducing mechanical signals into chemical
signals to regulate … Mechanical modulation of stiffness contributes to the use of MSCs in …
signals to regulate … Mechanical modulation of stiffness contributes to the use of MSCs in …
Mechanotransduction and stiffness-sensing: mechanisms and opportunities to control multiple molecular aspects of cell phenotype as a design cornerstone of cell …
M Selig, JC Lauer, ML Hart, B Rolauffs - International journal of molecular …, 2020 - mdpi.com
… under mechanical force input GEF-H1 shows an increased activity. … In this context substrate
mechanics control adipogenesis … AC from an anabolic growth factor into a catabolic cytokine […
mechanics control adipogenesis … AC from an anabolic growth factor into a catabolic cytokine […
Plantar mechanical stimulation attenuates protein synthesis decline in disused skeletal muscle via modulation of nitric oxide level
SA Tyganov, E Mochalova, S Belova, K Sharlo… - Scientific Reports, 2021 - nature.com
… effects of PMS on anabolic signaling pathways in rat soleus … ; changes in signaling pathways
regulating protein turnover as … Divergent effects of nitric oxide inhibition with different activity …
regulating protein turnover as … Divergent effects of nitric oxide inhibition with different activity …
[HTML][HTML] Cellular modulation by the mechanical cues from biomaterials for tissue engineering
Q Wei, S Wang, F Han, H Wang, W Zhang… - Biomaterials …, 2021 - ncbi.nlm.nih.gov
… The mechanical loads generated by these physical activities regulate tissue homeostasis
through … found that mechanical overload induced the imbalance of anabolism and …
through … found that mechanical overload induced the imbalance of anabolism and …
Mechanism and physical activities in bone-skeletal muscle crosstalk
Z Zhao, K Yan, Q Guan, Q Guo, C Zhao - Frontiers in Endocrinology, 2024 - frontiersin.org
… physical activity of the whole body, a mechanical sensor, and a secretory organ regulating
remote … IGF-1 functions as a growth factor and regulator affecting the catabolic and anabolic …
remote … IGF-1 functions as a growth factor and regulator affecting the catabolic and anabolic …
Yes-associated protein nuclear translocation promotes anabolic activity in human articular chondrocytes
… mechanical loading leads to increased catabolic activity and … translate external mechanical
cues into signaling conduits … in response to anabolic and catabolic stimuli was regulated by …
cues into signaling conduits … in response to anabolic and catabolic stimuli was regulated by …
Mechanical loading modulates AMPK and mTOR signaling in myblasts
X Zhou, S Zhu, J Li, A Mateus, L Backman - bioRxiv, 2024 - biorxiv.org
… anabolic response to resistance exercise, while AMPK is activated during 49 endurance
exercises to activate catabolic … and morphology are known to be regulated by the cytoskeleton […
exercises to activate catabolic … and morphology are known to be regulated by the cytoskeleton […
Molecular mechanisms of mechanical load-induced osteoarthritis
T Fang, X Zhou, M Jin, J Nie, XI Li - International Orthopaedics, 2021 - Springer
… that detect mechanical stress and regulate downstream signal … associated with modulation
of mechanical pain in OA. … The main biological activity of primary cilia is the intraflagellar …
of mechanical pain in OA. … The main biological activity of primary cilia is the intraflagellar …