… The prevalence of non-alcoholic fatty liver disease (NAFLD), one of the most common … were:
“non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, insulin resistance, metabolic …

… This review will describe the molecular mechanisms of inflammation and hepatic fibrosis in
IR, … Practice Guidelines for the management of non-alcoholic fatty liver disease. J. Hepatol. …

… chronic liver disease and posing a substantial public health challenge. NAFLD is associated
with higher insulin resistance (IR) levels, a key pathophysiological mechanism contributing …

… activator of PDH [46], changes in intracellular pyruvate availability likely represent another
important mechanism linking insulin resistance with hepatic PDH and mitochondrial function. …

Currently, Non-Alcoholic Fatty Liver Disease (NAFLD) is the most prevalent form of chronic
liver disease in children and adolescents worldwide. Simultaneously to the epidemic …

… In this review, we discuss the sites and mechanisms of insulin action and … mechanisms of
insulin action and IR-related impairment along the spectrum of NAFLD, from simple steatosis to …

… Both non-alcoholic fatty liver disease (NAFLD) and diabetes (… insulin concentrations, hepatic
insulin resistance, high … by insulin, but in presence of insulin resistance this mechanism is …

… pathway-selective hepatic insulin resistance hypothesis. In humans, hepatic DNL and
insulin resistance travel together: Hepatic DNL is increased in patients with NAFLD (42,43) and …

… appropriate term—MAFLD (metabolic associated fatty liver disease)—to replace NAFLD [9]. …
mechanisms of NAFLD development and its close link with insulin resistance. We will also …

… the complex mechanism underlying the development of non-alcoholic fatty liver disease (NAFLD), …
The term non-alcoholic fatty liver disease (NAFLD) was coined by Ludwig in 1980 to …