In silico predictions on the possible mechanism of action of selected bioactive compounds against breast cancer

A Muhammad, BS Katsayal, GE Forcados… - In Silico …, 2020 - Springer
possible mechanism of action of these xenobiotics to guide in vitro and in vivo studies in
breast cancer… resources that could result in futile in vitro and in vivo experiments. Hence, in this …

[HTML][HTML] Role of phytochemicals in cancer chemoprevention: Insights

BP George, R Chandran, H Abrahamse - Antioxidants, 2021 - mdpi.com
possible use in the prevention of cancers over the years. The increasing volume of in vitro and
in vivo data on the cancer chemopreventive … CYP1B1 and a mechanism-based inhibitor of …

The mechanism of dioscin preventing lung cancer based on network pharmacology and experimental validation

P Xi, Y Niu, Y Zhang, W Li, F Gao, W Gu, F Kui… - Journal of …, 2022 - Elsevier
… This study is to identify the prevention effect of dioscin on lung cancer and explore its key
mechanism based … Here, we reported that dioscin could prevent lung cancer in vitro and in vivo. …

Pomegranate peel and its anticancer activity: A mechanism-based review

T Usha, SK Middha, KR Sidhalinghamurthy - Plant-derived Bioactives …, 2020 - Springer
… The current chapter is aiming to understand various model systems (in silico, in vitro, and
in vivo), employed for studying its anti-cancerous properties and diverse molecular effects …

[HTML][HTML] Plant natural products: Promising resources for cancer chemoprevention

L Ma, M Zhang, R Zhao, D Wang, Y Ma, L Ai - Molecules, 2021 - mdpi.com
… Actually, there is an urgent need to develop the mechanism-based approaches/strategies …
Both in vivo and in vitro studies were involved in this review. The references of these articles …

Bioactive Polyphenols as promising natural medicinal agents against cancer: the emerging trends and prospective goals

O Prakash, S Usmani, A Gupta, R Singh… - Current Bioactive …, 2020 - ingentaconnect.com
… Accumulating the therapeutic evidence from the available in-vitro and in-vivo investigations
has proven the noteworthy anti-cancer potential of bioactive polyphenols. In the current study…

[HTML][HTML] Molecular and cellular mechanisms of propolis and its polyphenolic compounds against cancer

N Oršolić, M Jazvinšćak Jembrek - International journal of molecular …, 2022 - mdpi.com
… in vitro and in vivo studies has shown that flavonoids act as chemopreventive agents and
increase the efficacy of chemotherapy and radiotherapy in various cancers by regulating the …

[HTML][HTML] Mechanism-driven and clinically focused development of botanical foods as multitarget anticancer medicine: Collective perspectives and insights from …

X Wang, YS Chan, K Wong, R Yoshitake, D Sadava… - Cancers, 2023 - mdpi.com
… suggests developing a mechanism-based and clinically relevant in vitro biological assay …
mechanism of action and/or relate to the surrogate diagnostic biomarker of the cancers [30]. …

[HTML][HTML] … chemopreventive agent, enhances the antitumor effect of 5-FU against breast cancer and inhibits tumor growth and angiogenesis in Ehrlich solid tumor

NH Shehatta, TM Okda, GA Omran… - Biomedicine & …, 2022 - Elsevier
… of cancers, including breast cancer. The present study aimed to explore the chemopreventive
and … the antitumor effect of 5-FU on breast cancer using the Ehrlich solid tumor-mice model. …

Selenium-based novel epigenetic regulators offer effective chemotherapeutic alternative with wider safety margins in experimental colorectal cancer

P Ghanghas, M Sharma, D Desai, K Raza… - … Trace Element Research, 2021 - Springer
… Thus, the present study is the first in vivo report aimed to explore the anti-tumorigenic role
of Se analog of SAHA called SelSA-1 in DMH-induced experimental colon cancer in Balb/c …