Insights into new mechanisms and models of cancer stem cell multidrug resistance
Y Garcia-Mayea, C Mir, F Masson, R Paciucci… - Seminars in cancer …, 2020 - Elsevier
… and resistant disease. Targeting resistant cancers is a major challenge in oncology; however…
and increase life expectancy, relapse and multidrug resistance (MDR) ultimately remain the …
and increase life expectancy, relapse and multidrug resistance (MDR) ultimately remain the …
[HTML][HTML] Anticancer drug resistance: An update and perspective
R Nussinov, CJ Tsai, H Jang - Drug Resistance Updates, 2021 - Elsevier
… discuss the molecular mechanisms underlying drug resistance while focusing on those
emerging to common targeted cancer drivers. We also address questions of why cancers with a …
emerging to common targeted cancer drivers. We also address questions of why cancers with a …
Multidrug resistance in cancer: understanding molecular mechanisms, immunoprevention and therapeutic approaches
… drug resistance mechanisms in cancer. Cancer cells develop resistance to anticancer
agents (drugs… Furthermore, EVs derived from drug-resistant cancer cells may also serve as …
agents (drugs… Furthermore, EVs derived from drug-resistant cancer cells may also serve as …
Surmounting cancer drug resistance: New insights from the perspective of N6-methyladenosine RNA modification
… In this review, we discuss the molecular mechanisms underlying the m 6 A modification in
regulating anticancer drug resistance through modulation of drug-target interaction and drug-…
regulating anticancer drug resistance through modulation of drug-target interaction and drug-…
Targeting MAPK signaling in cancer: mechanisms of drug resistance and sensitivity
… drug sensitivity and resistance in cancer. We briefly discuss new findings in the extracellular
signaling-regulated kinase (ERK) pathway, but mainly focus on the mechanisms … of cancer …
signaling-regulated kinase (ERK) pathway, but mainly focus on the mechanisms … of cancer …
Challenges and opportunities in cancer drug resistance
RA Ward, S Fawell, N Floc'h, V Flemington… - Chemical …, 2020 - ACS Publications
… they can offer valuable insights into understanding the mechanism of resistance and how to
… In addition, some mutations which cause resistance can be from additional effects unrelated …
… In addition, some mutations which cause resistance can be from additional effects unrelated …
Epitranscriptomics and epiproteomics in cancer drug resistance: therapeutic implications
… Drug resistance is a major hurdle in cancer treatment and a key cause … drug resistance. In
this review article, we summarized the recent progress in overcoming cancer drug resistance …
this review article, we summarized the recent progress in overcoming cancer drug resistance …
Practical classification of triple-negative breast cancer: intratumoral heterogeneity, mechanisms of drug resistance, and novel therapies
A Marra, D Trapani, G Viale, C Criscitiello… - … breast cancer, 2020 - nature.com
… Furthermore, we point out current and emerging biomarker-driven treatments for TNBC
subtypes and describe the most common mechanisms of drug resistance for approved therapies …
subtypes and describe the most common mechanisms of drug resistance for approved therapies …
Cancer drug resistance induced by EMT: novel therapeutic strategies
J De Las Rivas, A Brozovic, S Izraely, A Casas-Pais… - Archives of …, 2021 - Springer
… importance of tumour microenvironment and EMT in multidrug resistance (MDR), this issue
will … in depth into the molecular mechanism by which EMT induce therapy resistance and how …
will … in depth into the molecular mechanism by which EMT induce therapy resistance and how …
Non-genetic mechanisms of therapeutic resistance in cancer
JC Marine, SJ Dawson, MA Dawson - Nature Reviews Cancer, 2020 - nature.com
… a | Genetic mechanisms of drug resistance include mechanisms … insights into the key
determinants that mediate neuroendocrine transformation in both lung cancer and prostate cancer, …
determinants that mediate neuroendocrine transformation in both lung cancer and prostate cancer, …