[HTML][HTML] Recent advances in genome editing of stem cells for drug discovery and therapeutic application
J Lee, D Bayarsaikhan, G Bayarsaikhan, JS Kim… - Pharmacology & …, 2020 - Elsevier
… diseases caused by single nucleotide polymorphisms (SNPs), by … fused with an engineered
reverse transcriptase (RT) and … to HIV-1 infection, while heterozygosity is associated with …
reverse transcriptase (RT) and … to HIV-1 infection, while heterozygosity is associated with …
The S180R Human Germline Variant of DNA Polymerase β Exhibits Low Fidelity and the Potential to Drive Cancer Formation
D Sawyer - 2024 - repository.arizona.edu
… The first subdomain is the thumb subdomain that consists of residues 91-149 and has also
been cited as the “D-subdomain” due to its main function being DNA binding. An additional …
been cited as the “D-subdomain” due to its main function being DNA binding. An additional …
Role of selective autophagy receptors in MHC-II-restricted antigen presentation and their hijacking by viruses to escape T cell immunity
G Sarango - 2023 - theses.hal.science
… Interestingly, TRIM5 binds to the HIV-1 capsid protein550 and … and are the most polymorphic
genetic system in vertebrates (… of the α1 and α2 sub-domains, which control the nature of …
genetic system in vertebrates (… of the α1 and α2 sub-domains, which control the nature of …
Mutation in a sars-cov-2 haplotype from sub-antarctic chile reveals new insights into the spike's dynamics
J González-Puelma, J Aldridge, M Montes de Oca… - Viruses, 2021 - mdpi.com
… Reverse transcription of viral RNA was performed using … gene, two of these polymorphisms
refer to amino acid changes (… between S1 and S2 subdomains result in different ratios of “up” …
refer to amino acid changes (… between S1 and S2 subdomains result in different ratios of “up” …
[图书][B] A Mechanistic Framework for Telomerase Kinetics Identifies New Opportunities for Therapeutic Interventions
WM Hernández-Sánchez - 2020 - search.proquest.com
… , with the reverse transcriptase domains of retrotransposons … respect to the palm and finger
subdomains of viral RNA and … are associated with single nucleotide polymorphisms within TR …
subdomains of viral RNA and … are associated with single nucleotide polymorphisms within TR …
Multi'omics integration of the HIV airway epithelium: integration of the microbiome, transcriptome and methylome
MS Jude - 2021 - open.library.ubc.ca
… , however the exact mechanism of disease progression is still … common and infectious strain
is HIV-1. HIV infection is a … -CpG), presence of single nucleotide polymorphisms in the probe …
is HIV-1. HIV infection is a … -CpG), presence of single nucleotide polymorphisms in the probe …
[图书][B] Oncoviruses: Cellular and Molecular Virology
A Yaro - 2021 - books.google.com
… In HIV-associated cancers, it has been shown that HIV-1 … method is called random amplified
polymorphism DNA (RAPD)… , replication takes place through reverse transcription of an RNA …
polymorphism DNA (RAPD)… , replication takes place through reverse transcription of an RNA …
[PDF][PDF] Directed evolution of Polymerases and its application in Sequence Saturation Mutagenesis
ME Chung - 2021 - publications.rwth-aachen.de
… are finally recovered by reverse transcription followed by PCR … The fingers, palm, and thumb
subdomains are indicated in … the detection of single nucleotide polymorphisms (SNPs) and …
subdomains are indicated in … the detection of single nucleotide polymorphisms (SNPs) and …
Various aspects of a gene editing system—crispr–cas9
E Janik, M Niemcewicz, M Ceremuga… - International journal of …, 2020 - mdpi.com
… -II and RuvC-III subdomains and cleaves the nontarget strand. … ) nickase fused to engineered
reverse transcriptase (RT). … A new therapeutic application may be eliminating HIV-1 DNA …
reverse transcriptase (RT). … A new therapeutic application may be eliminating HIV-1 DNA …
An Overview of Gene Editing Modalities and Related Non-clinical Testing Considerations
S Vats, C Ballesteros, S Hung… - International …, 2023 - journals.sagepub.com
… coding), pol (reverse transcription/host integration) … polymorphisms (SNP) in human T cell
leukemia virus-1 (HTLV-1), bovine leukemia virus (BLV), human immunodeficiency virus (HIV-1…
leukemia virus-1 (HTLV-1), bovine leukemia virus (BLV), human immunodeficiency virus (HIV-1…