Molecular Characterisation of Flavivirus Interactions with the Host Innate Immune Response

RC Coldbeck-Shackley - 2021 - digital.library.adelaide.edu.au
… In this thesis we explore the virus dependent mechanisms … Moreover, a single nucleotide
polymorphism resulting in an … up of three subdomains the finger, palm, and thumb. This domain …

Understanding the viral diversity of Hepatitis B virus in Saudi Arabia using Next Generation Sequencing (NGS)

AA Alessa - 2021 - theses.gla.ac.uk
Next-generation sequencing (NGS) is a powerful method for detecting the viral mutations.
The aim of this study was divided into two main sections; initially developed a protocol for …

[HTML][HTML] 2021 PROTEIN SOCIETY DIVERSITY AWARD WINNERS

S Aljoudi, PI Ayotunde, A Chang-Gonzalez… - ncbi.nlm.nih.gov
… In order to elucidate the mechanism for how HypD performs … Natural polymorphisms affect
structure and function of gC1q … change and the key subdomain involved in strand separation. …

[HTML][HTML] Mechanisms of binding specificity among bHLH transcription factors

X de Martin, R Sodaei, G Santpere - International Journal of Molecular …, 2021 - mdpi.com
selection acting on a group of binding sites [4]. Moreover, a fraction of genomic variants falling
on TFBS are associatedselection can be observed when leveraging polymorphism data …

[图书][B] Post-transcriptional Gene Regulation in Human Disease

BP Jain, SK Goswami, T Sharma - 2022 - books.google.com
mechanisms … , associated epigenetic mechanisms, the role of RNA binding proteins, the
evolution of post-transcriptional gene regulation, and methods to study these mechanisms. The …

[图书][B] RNA as a Drug Target: The Next Frontier for Medicinal Chemistry

R Mannhold, H Buschmann, J Holenz - 2024 - books.google.com
… By a mechanism analogous to targeted protein degradation … The Rev Response Element
(RRE) of HIV-1, which interacts … can be read out by reverse transcription experiments [47]. …

Molecular signals of arms race evolution between RNA viruses and their hosts

S Lytras - 2023 - theses.gla.ac.uk
… Furthermore, the primate paralogue of APOBEC3G, APOBEC3F, can also restrict HIV-1 but
Vif also counteracts this protein through a distinct mechanism to that of APOBEC3G evasion (…

Identification of Novel Viral Interacting Proteins through the Detection of Genetic INNovations (DGINN) combined with functional assays

L Picard - 2020 - theses.hal.science
… TMEM140s have no effect on HIV-1 replication during early or … c — Balancing selection
maintains polymorphism in the … for reverse transcription, becoming the Reverse Transcription

[图书][B] Noncoding Mechanisms in NF-κB Driven Vascular Endothelial Cell Inflammation

N Khyzha - 2020 - search.proquest.com
… Single nucleotide polymorphism STARR seq Self transcribing active regulatory region
sequencing STAU1 Staufen1 TAD Topologically associated domain TALEN Transcription activator…

[HTML][HTML] Krüpple-like factors in cardiomyopathy: emerging player and therapeutic opportunities

LK Gui, HJ Liu, LJ Jin, XC Peng - Frontiers in Cardiovascular Medicine, 2024 - frontiersin.org
… Research has classified KLF1 TAD into two functional subdomains, … In their study, they
genotyped 33 single nucleotide polymorphisms (… Here, we review the mechanisms underlying the …