Oxalate-induced apoptosis through ERS-ROS–NF-κB signalling pathway in renal tubular epithelial cell

S Ming, J Tian, K Ma, C Pei, L Li, Z Wang, Z Fang… - Molecular …, 2022 - Springer
… In this study, we investigated the roles of endoplasmic … pathogenesis of oxalate-induced
renal tubular epithelial cell injury and … information transcription mediated by various cell stimuli; …

[HTML][HTML] The protective effect of caffeine against oxalate-induced epithelial-mesenchymal transition in renal tubular cells via mitochondrial preservation

R Kanlaya, C Subkod, S Nanthawuttiphan… - Biomedicine & …, 2024 - Elsevier
… Finally, we have addressed that the oxalate-induced renal cell deteriorations were
mediated through the Snai1 EMT-related gene as all the effects of oxalate on suppression of …

In vitro cell culture models of hyperoxaluric states: Calcium oxalate and renal epithelial cell interactions

Renal cell injury is also mediated through strong inflammatory immune response.
Significant immune response to calcium oxalate crystals is also mediated by … that oxalate-induced

[HTML][HTML] Sirt1 inhibits kidney stones formation by attenuating calcium oxalate-induced cell injury

QL Ye, DM Wang, X Wang, ZQ Zhang, QX Tian… - Chemico-Biological …, 2021 - Elsevier
renal cell injury. This study aims to explore the relationship between Sirt1 and CaOx kidney
stone formation and the underlying mechanism. … Sirt1 plays an important role in mediating

Sodium oxalate-induced acute kidney injury associated with glomerular and tubulointerstitial damage in rats

L de Araújo, JM Costa-Pessoa, MC De Ponte… - Frontiers in …, 2020 - frontiersin.org
Acute crystalline nephropathy is closely related to tubulointerstitial injury, but few studies
have investigated glomerular changes in this condition. Thus, in the current study, we …

Protective roles of trigonelline against oxalate-induced epithelial-to-mesenchymal transition in renal tubular epithelial cells: an in vitro study

P Peerapen, V Thongboonkerd - Food and Chemical Toxicology, 2020 - Elsevier
… prevent oxalate-induced cell migration. The result from our present study was supported by
several previous studies reporting that EMT induced epithelial cell migration in diverse cells (…

Oxalate homeostasis

T Ermer, L Nazzal, MC Tio, S Waikar… - Nature Reviews …, 2023 - nature.com
oxalate-inducedmediate HCO 3 – rather than oxalate influx in exchange for intracellular
sulfate in the proximal tubule 77 . No direct evidence of a role for SLC26A1 in mediating oxalate …

Ursolic acid treats renal tubular epithelial cell damage induced by calcium oxalate monohydrate via inhibiting oxidative stress and inflammation

Z Jia, W Li, P Bian, L Yang, H Liu, D Pan, Z Dou - Bioengineered, 2021 - Taylor & Francis
… This process is mediated by the SLC26A anion exchanger … effect on oxalate-induced renal
tubular epithelial cell injury. In order to … in renal tissue and knockdown COM-induced renal cell

[HTML][HTML] Caffeine prevents oxalate-induced epithelial-mesenchymal transition of renal tubular cells by its anti-oxidative property through activation of Nrf2 signaling …

R Kanlaya, C Subkod, S Nanthawuttiphan… - Biomedicine & …, 2021 - Elsevier
… abolish such protective effects of caffeine on oxalate-induced EMT. Our data indicate that
the renoprotective effects of caffeine against oxalate-induced EMT is mediated, at least in part, …

[HTML][HTML] Theaflavin protects against oxalate calcium-induced kidney oxidative stress injury via upregulation of SIRT1

T Ye, X Yang, H Liu, P Lv, H Lu, K Jiang… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
… how TF increased the SIRT1 expression to exert a nephroprotective role, we detected …
mediated kidney injury might promote stone formation through increasing the number of cellular