Deciphering the pathways to antiviral innate immunity and inflammation
Q Yang, HB Shu - Advances in immunology, 2020 - Elsevier
… The antiviral innate immune and inflammatory responses are … We identified several proteins
that modulate TBK1 activity. … the mechanisms of TLR3/4-mediated innate immune and …
that modulate TBK1 activity. … the mechanisms of TLR3/4-mediated innate immune and …
[PDF][PDF] APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes
SM de Leeuw, AWT Kirschner, K Lindner, R Rust… - Stem cell reports, 2022 - cell.com
… and immune regulation indicates that it is not a mere decrease of function in APOE4 cells:
APOE2, APOE3, and APOE4 iAstrocytes may utilize different mechanisms altogether. Further …
APOE2, APOE3, and APOE4 iAstrocytes may utilize different mechanisms altogether. Further …
The transmembrane endoplasmic reticulum–associated E3 ubiquitin ligase TRIM13 restrains the pathogenic-DNA–triggered inflammatory response
X Li, Z Yu, Q Fang, M Yang, J Huang, Z Li, J Wang… - Science …, 2022 - science.org
… The E3 ubiquitin ligases ring finger … , modulation of STING ubiquitylation by E3 ubiquitin
ligases or deubiquitinases represents a kind of key negative mechanism, whereas several E3 …
ligases or deubiquitinases represents a kind of key negative mechanism, whereas several E3 …
The role of ubiquitin E3 ligase in atherosclerosis
ZX Zhou, Z Ren, BJ Yan, SL Qu… - Current Medicinal …, 2021 - ingentaconnect.com
… as abnormal cholesterol metabolism and vascular inflammatory responses. Subsequently,
the … posttranslational regulatory mechanisms such as ubiquitination modulate the localization, …
the … posttranslational regulatory mechanisms such as ubiquitination modulate the localization, …
A novel polysaccharide obtained from Siraitia grosvenorii alleviates inflammatory responses in a diabetic nephropathy mouse model via the TLR4-NF-κB pathway
P Gong, D Cui, Y Guo, M Wang, Z Wang, Z Huang… - Food & Function, 2021 - pubs.rsc.org
… the underlying molecular mechanisms of inflammation and … −1 ) exhibited good
inflammation-modulating activity. In addition… the inflammatory and antioxidant modulating effects of …
inflammation-modulating activity. In addition… the inflammatory and antioxidant modulating effects of …
E3 ubiquitin ligase Casitas B lineage lymphoma-b and its potential therapeutic implications for immunotherapy
D Jafari, MJ Mousavi… - … Immunology, 2021 - academic.oup.com
… mechanisms of the immune system. Among these, the … the Cbl E3 ligase family c-Cbl has a
central mediator in modulating the DC … inflammatory response to OVA-induced allergic airway …
central mediator in modulating the DC … inflammatory response to OVA-induced allergic airway …
Salmonella Typhimurium and inflammation: a pathogen-centric affair
JE Galán - Nature Reviews Microbiology, 2021 - nature.com
… mechanisms that are aimed at recovering host homeostasis after the inflammatory response.
For … Typhimurium modulates the inflammatory response are a remarkable example of the …
For … Typhimurium modulates the inflammatory response are a remarkable example of the …
[HTML][HTML] 14-3-3 modulation of the inflammatory response
… the mechanisms underpinning the inflammatory response [1]. … and the mechanisms
associated with chronic inflammation for … and the treatment of inflammation-related conditions. …
associated with chronic inflammation for … and the treatment of inflammation-related conditions. …
K63 ubiquitination in immune signaling
C Madiraju, JP Novack, JC Reed, S Matsuzawa - Trends in Immunology, 2022 - cell.com
… inflammatory responses (left). FOXP3-dependent K63 ubiquitination of target substrates
regulates immune tolerance mechanisms … that other important modulators of immune responses, …
regulates immune tolerance mechanisms … that other important modulators of immune responses, …
[HTML][HTML] Mycobacterium tuberculosis protein PE6 (Rv0335c), a novel TLR4 agonist, evokes an inflammatory response and modulates the cell death pathways in …
… These findings unravel novel mechanisms exploited by PE6 protein to subdue host immunity,
thereby providing insights relevant to a better understanding of host–pathogen interaction …
thereby providing insights relevant to a better understanding of host–pathogen interaction …