Role of specialized pro-resolving mediators in neuropathic pain
A Leuti, M Fava, N Pellegrini… - Frontiers in …, 2021 - frontiersin.org
… SPMs on neuropathic pain (A): SPMs modulate the genesis of neuropathic pain by acting on
… Chemical structure of the main SPMs involved in neuropathic pain (B). SPM receptors, with …
… Chemical structure of the main SPMs involved in neuropathic pain (B). SPM receptors, with …
Mediators of neuropathic pain; focus on spinal microglia, CSF-1, BDNF, CCL21, TNF-α, Wnt ligands, and interleukin 1β
… A variety of chemical mediators effect communication between the various cell types … of
pathological pain. We focus on mediators that affect spinal microglia, mediators released from …
pathological pain. We focus on mediators that affect spinal microglia, mediators released from …
Mechanisms for reducing neuropathic pain
DP Kuffler - Molecular Neurobiology, 2020 - Springer
… and mediators contributing to the development and maintenance of neuropathic pain are …
, inducing the release of anti-inflammatory mediators, and silencing the chronically electrically …
, inducing the release of anti-inflammatory mediators, and silencing the chronically electrically …
Neuroinflammation, oxidative stress and their interplay in neuropathic pain: Focus on specialized pro-resolving mediators and NADPH oxidase inhibitors as potential …
L Teixeira-Santos, A Albino-Teixeira, D Pinho - Pharmacological Research, 2020 - Elsevier
… Neuropathic pain (NP) is a chronic condition that results from a lesion or disease of the …
of exogenous specialized pro-resolving mediators (SPMs) ameliorates NP pathophysiology. …
of exogenous specialized pro-resolving mediators (SPMs) ameliorates NP pathophysiology. …
Pain-resolving immune mechanisms in neuropathic pain
… In summary, an emerging picture indicates that specific innate immune cell subtypes and
associated mediators promote the resolution of neuropathic pain. Several processes are …
associated mediators promote the resolution of neuropathic pain. Several processes are …
Neuropathic pain: from mechanisms to treatment
… They subsequently reported that SOM+ neurons are largely sufficient and necessary to
mediate mechanical hypersensitivity in neuropathic pain (119). Peirs et al. (381) implicated a …
mediate mechanical hypersensitivity in neuropathic pain (119). Peirs et al. (381) implicated a …
Anti-neuropathic pain activity of a cationic palladium (II) dithiocarbamate by suppressing the inflammatory mediators in paclitaxel-induced neuropathic pain model
… Neuropathic pain is a chronic pain state that negatively impacts the quality of life. Currently,
available therapies for the treatment of neuropathic pain often … suppress neuropathic pain. …
available therapies for the treatment of neuropathic pain often … suppress neuropathic pain. …
Peripheral neuropathic pain: from experimental models to potential therapeutic targets in dorsal root ganglion neurons
TY Yeh, IW Luo, YL Hsieh, TJ Tseng, H Chiang… - Cells, 2020 - mdpi.com
… In this review, we focus on molecular mechanisms and mediators of neuropathic pain …
mediators and their modification and regulations provide excellent targets for neuropathic pain …
mediators and their modification and regulations provide excellent targets for neuropathic pain …
Profiling of inflammatory mediators in the synovial fluid related to pain in knee osteoarthritis
L Li, Z Li, Y Li, X Hu, Y Zhang, P Fan - BMC Musculoskeletal disorders, 2020 - Springer
… of SF inflammatory mediators in neuropathic pain is not clear. … mediators associated with
nociceptive and neuropathic pain … between neuropathic pain and SF inflammatory mediators. …
nociceptive and neuropathic pain … between neuropathic pain and SF inflammatory mediators. …
[HTML][HTML] Neuromodulation, specialized proresolving mediators, and resolution of pain
… Recent studies suggest that SPMs inhibit inflammatory pain, postoperative pain, neuropathic
pain, and cancer pain in rodent models via immune, glial, and neuronal modulations. It is …
pain, and cancer pain in rodent models via immune, glial, and neuronal modulations. It is …
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