Mesenchymal stem cell therapy improves erectile dysfunction in experimental spinal cord injury

Ö Albayrak, TE Şener, M Erşahin… - … Journal of Impotence …, 2020 - nature.com
Spinal cord injury caused decrease on NGF and n-NOS … The ICP/MAP value in vehicle-treated
SCI rats was found to be … MSC treatment effects on erectile function in SCI injured rats. …

Erectile dysfunction: pharmacological pathways with understudied potentials

DR Adam, MM Alem - Biomedicines, 2022 - mdpi.com
… , melatonin improved erectile function via its antioxidant properties in other animal models
such as rats with spinal cord injuries [69] and ratstadalafil/placebo, respectively. Both studies …

Erectile Dysfunctions

SMK Aghamir, F Guitynavard - Stem Cells in Urology, 2020 - Springer
… that daily intake of tadalafil (5 mg) helps improve endothelial cell function in ED patients, …
effect of melatonin on the prevention of ED in a DM rat model was beneficial. Chronic melatonin

Nrf2 enhances the therapeutic efficiency of adipose-derived stem cells in the treatment of neurogenic erectile dysfunction in a rat model

S Yang, W Shi, Q Liu, Y Song, J Fang - Basic and Clinical Andrology, 2023 - Springer
… , so as to improve the therapeutic effect of MSCs on nerve injured-induced ED rat models. …
The impairment of erectile function after nerve injury is partly due to changes in the smooth …

Melatonin, a natural antioxidant therapy in spinal cord injury

L Xie, H Wu, X Huang, T Yu - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
… ischemic spinal cord injured rats, while pretreatment with melatonintherapy of melatonin
and tadalafil (a medicine for erection problems) is more effective in restoring erectile function

Tadalafil alleviates cisplatin-induced reproductive toxicity through the activation of the Nrf2/HO-1 pathway and the inhibition of oxidative stress and apoptosis in male …

BA Abdel-Wahab, SA Alkahtani, EAM Elagab - Reproductive Toxicology, 2020 - Elsevier
Tadalafil (TDF), is a long-acting phosphodiesterase-5 (PDE5) inhibitor commonly used as
treatment for erectile dysfunction… , which are associated with improved epididymal sperm count …

… Gel-Loaded Phosphodiesterase Inhibitors (Sildenafil, Vardenafil, and Tadalafil): Prospects for Topical Penile Therapy of Tadalafil for Treatment of Erectile Dysfunction

SA Mohamed, RR Rofaeil, H Salem, M Elrehany… - Gels, 2023 - mdpi.com
Tadalafil improves the patient’s sexual confidence directly through improving erectile function
… orally and topically treated male rats with tadalafil. This indicated that both oral and topical …

Effect of PDE 5 Inhibitor-Avanafil on Renal Ischemia/Reperfusion Injury in Rats.

TN YÜKSEL, Z HALICI, C KAYA… - Namık Kemal Tıp …, 2023 - search.ebscohost.com
treatment improved the increase in the mRNA expressions of IL-1β, NF-κB, and TNF-α in
kidney tissues induced ischemia/reperfusion injury… primary treatment of erectile dysfunction as …

Research progress on the therapeutic application of extracellular vesicles in erectile dysfunction

X Zhang, M Yang, X Chen, M Lu - Sexual Medicine Reviews, 2024 - academic.oup.com
… by sildenafil and tadalafil, is still the first-line treatment of ED.… prevents fibrosis and improves
erectile function in a rat model of … Melatonin-primed mesenchymal stem cells–derived small …

Transcranial photobiomodulation therapy for sexual dysfunction associated with depression or induced by antidepressant medications

F Salehpour, M Khademi, F Vahedifard, P Cassano - Photonics, 2022 - mdpi.com
tadalafil) have been shown to be helpful in treating erectile … (by 50%) in naive mice, immediately
after turning on the laser. In … Putatively, the inhibitory role of melatonin on sexual function