Correlation of brain flow variables and metabolic crisis: a prospective study in patients with severe traumatic brain injury

CP Marini, C Stoller, J McNelis, V Del Deo… - … Journal of Trauma and …, 2022 - Springer
… to prevent secondary brain ischemia from the activation of the … common type of brain flow
oxygen crisis is a combination of … associated with severe metabolic crisis and ischemia as the …

[HTML][HTML] Brain Shock—Toward Pathophysiologic Phenotyping in Traumatic Brain Injury

C Lazaridis - Critical care explorations, 2022 - journals.lww.com
metabolism, energy crisis, and if not reversed tissue necrosis. Shock results from a
number of often combiningcerebral energy crisis—that is, ischemia due to low CPP/CBF—is …

Microdialysis-based classifications of abnormal metabolic states after traumatic brain injury: a systematic review of the literature

S Venturini, F Bhatti, I Timofeev… - Journal of …, 2023 - liebertpub.com
Metabolic crisis without brain ischemia is common after traumatic brain injury: a combined
… Focally perfused succinate potentiates brain metabolism in head injury patients. J Cereb …

Nutrition therapy, glucose control, and brain metabolism in traumatic brain injury: a multimodal monitoring approach

P Kurtz, EEM Rocha - Frontiers in Neuroscience, 2020 - frontiersin.org
… predictor of mortality after TBI, and together with the prevention … in coma secondary to head
injury present a hypermetabolic … detection of ischemia and metabolic crisis after TBI. The most …

Metabolic derangements are associated with impaired glucose delivery following traumatic brain injury

J Hermanides, YT Hong, M Trivedi, J Outtrim… - Brain, 2021 - academic.oup.com
… intracranial pressure monitoring following head injury within a … and oxygen metabolism in
the absence of ischaemia. Clinical … Using a combination of 18 F-FDG and 15 O PET, with brain

Revisiting ischemia after brain injury: oxygen may not be the only problem

G Harutyunyan, R Avitsian - Journal of Neurosurgical …, 2020 - journals.lww.com
… that metabolic crisis is cellular stress “without brain ischemia,” 2 also referred to as “nonischemic
oxidative metabolic … Similarly, in a study combining PET and cerebral microdialysis in a …

New insights into metabolism dysregulation after TBI

HC Oft, DW Simon, D Sun - Journal of neuroinflammation, 2024 - Springer
together, this narrative review summarizes published TBI-associated changes in glucose and
lipid metabolism, … state of “metabolic crisis” have distinguished low “fuel” (ischemic) states …

Mild traumatic brain injury increases vulnerability to cerebral ischemia in mice

ZM Weil, K Karelina, B Whitehead… - Experimental …, 2021 - Elsevier
metabolic physiology mediated poorer outcomes after TBI. … to exacerbate ischemic outcomes
by impairing metabolic and … rates than individuals without a history of head injury, but these …

Management of Severe Traumatic Brain Injury: A Practical Approach

DA Godoy, AA Khan, AM Rubiano - Neurological Emergencies: A Practical …, 2020 - Springer
… of metabolic crises have been recognized: type I or ischemic, … complex and mixed, and
global monitors of brain physiology … A new classification of head injury based on computerized …

Secondary cerebral ischemia at traumatic brain injury is more closely related to cerebrovascular reactivity impairment than to intracranial hypertension

M Dobrzeniecki, A Trofimov, D Martynov… - Intracranial Pressure …, 2021 - Springer
… Results: The deterioration of CVR in combination with the … the following features: severe
TBI within 6 h after a head injuryMetabolic crisis and inflammation in brain injury are also …