… NADH oxidation in submitochondrial particles, an indicator of complex I inhibition. Their
results corresponded closely with dehydrogenase activity in living cells measured by WST-1, a …

… of metformin in inhibiting OXPHOS in cancer patients remains uncertain. The available …
that metformin-induced STAT3 inhibition (at therapeutic doses) exerts antitumor effects by …

… The euglycemic effect of MTF is due to the inhibition of … to the inhibition of Complex I, although
this effect is obtained only at … seems to activate the mitochondrial electron transport chain, …

… on the effect of metformin on mitochondria and cellular … Metformin-induced activation of
AMPK was inhibitory to NF-κB pathways that were promoted by AGEs. Metformin’s inhibition of …

… Although metformin-induced inhibition of mitochondrial respiratory chain Complex I and …
The aim of this study was to explore the effects of different metformin concentrations on …

… the mitochondria contributes to its mild inhibitory effects on … exacerbate metformin-induced
apoptosis and mitochondrial … This uncertainty stems from its low concentration and short half…

… These effects were achieved through metformin-induced inhibition of HIF-1α activity and its
binding to the hypoxia-responsive elements (HRE) within the promoter region of these genes …

… through mitochondrial oxidative phosphorylation, by inhibiting the … showed that
metformin-induced mitochondrial division was … These results were verified by examining the …

… direct or indirect inhibition of mitochondrial complex I of the … Inhibition of complex I by metformin
in metabolic cells is … , to determine if metformin induced AMPK activity. Metformin did not …

… from the metformin-induced stabilization of the deactive form of … results from many factors,
including procedural errors, … 66 and direct inhibitory effect on the mitochondrial complex I. …