… We next validated the expression pattern of Mat2b in mouse oocytes and early embryos.
As shown in Fig. 2A, Mat2b is highly expressed in the GV and MII stages. The mRNA level of …

… Methionine adenosyltransferase 2A (MAT2A) is an essential … , which plays key roles in
zygotic genome activation (ZGA). … In conclusion, MAT2A is involved in regulating transcriptional …

… down-regulated after eIF1A knockdown in morula stage. In … of the key regulators of
mouse zygotic genome activation. … demonstrated that Methionine adenosyltransferase II (MAT2A…

… The methionine adenosyltransferase II (MAT) catalyzes the synthesis of S-… morula transition
and glucose is required for blastocyst formation [39]. Genes related to zygotic gene activation …

… To explore this, we study a mouse model of abnormal folate metabolism whereby the gene
… MTRR is a key enzyme required for the progression of folate and methionine metabolism, …

… is synthesised by Methionine adenosyltransferase II (MAT) [13]. … In mice, CL exposure resulted
in embryos arrested at morula … Our findings provide new insights of the regulated roles of …

… In addition, methionine modulated one-carbon metabolism … (CBS) and methionine
adenosyltransferase 2A (MAT2A), … MAT2A is indispensable for zygotic gene activation, morula-to-…

… controls the entry of onecarbon units into the methionine … via the enzyme methionine
adenosyltransferase (MAT) to … and in mouse embryos at the 1-cell, 2-cell, morula and blastocyst …

… product inhibitor or methionine antagonist during the first three days of culture affected bovine
embryo development to the morula stage [41,… MAT2A methionine adenosyltransferase 2A …

… how the process of methylation is regulated is important, as … embryo, 2-cell embryo, morula
and blastocysts. In MII eggs the … Zygote genome activation occurs at the 2-cell stage in mice (…