It is unprecedented: trial management during the COVID-19 pandemic and beyond

EJ Mitchell, K Ahmed, S Breeman, S Cotton… - Trials, 2020 - Springer
… and online networking events and wider experiences of trial … a surgical trial demonstrated
that holding online initial contact … new methodologies for training provides opportunities for trial

The pandemic of online research in times of COVID-19

J De Man, L Campbell, H Tabana, E Wouters - BMJ open, 2021 - bmjopen.bmj.com
methodological approach: the assessment of latent variables measured with rating scales in
online … has a long-standing track record of challenges and uncertainties, from setting up the …

Real-world data: a brief review of the methods, applications, challenges and opportunities

F Liu, D Panagiotakos - BMC Medical Research Methodology, 2022 - Springer
trials are trials designed to test the effectiveness of an intervention in the real-world clinical
setting. Pragmatic trials … RWD, new guidelines and methodologies are developed to mitigate …

Looking at the 'field'through a Zoom lens: Methodological reflections on conducting online research during a global pandemic

M Howlett - Qualitative Research, 2022 - journals.sagepub.com
… As such, it is important to consider how these different methodological approaches challenge
methodological and epistemological questions through reflections on conducting online

Legal, regulatory, and practical issues to consider when adopting decentralized clinical trials: recommendations from the clinical trials transformation initiative

M Apostolaros, D Babaian, A Corneli, A Forrest… - … innovation & regulatory …, 2020 - Springer
… features within a traditional trial by introducing remote methodologies with an amendment to
… the trial to ensure compliance with applicable laws. Sponsors should consider using online

From challenge to opportunity: virtual qualitative research during COVID-19 and beyond

S Keen, M Lomeli-Rodriguez… - International Journal of …, 2022 - journals.sagepub.com
… validity and enhance interview interactions within specific methodologies, this paper turns
to … Just as online therapy may reduce access barriers by normalising it within wider online

Challenges in meta-analyses with observational studies

S Metelli, A Chaimani - BMJ Ment Health, 2020 - mentalhealth.bmj.com
… considered suboptimal to those involving randomised controlled trials (RCTs) only. This is
due … amount of clinical and methodological heterogeneity and assessment of possible biases. …

Impact of blinding on estimated treatment effects in randomised clinical trials: meta-epidemiological study

H Moustgaard, GL Clayton, HE Jones, I Boutron… - bmj, 2020 - bmj.com
… designed to answer a methodological challenge that was not directly dependent on patient
priorities, experiences, or participant preferences. The methodological expertise required to …

Let's talk virtual! Online focus group facilitation for the modern researcher

M Halliday, D Mill, J Johnson, K Lee - Research in Social and …, 2021 - Elsevier
… Our study demonstrates that an entirely online approach to focus group methodology is …
These break out rooms were used by the support researcher to test and trial a participant's audio …

Face-to-face compared with online collected accounts of health and illness experiences: A scoping review

L Davies, KL LeClair, P Bagley… - Qualitative Health …, 2020 - journals.sagepub.com
… purposeful and evidence-based decisions about when online and face-to-face approaches
… overcoming particular methodological challenges. Continued studies comparing online and …