Inflammation: Biochemistry, cellular targets, anti-inflammatory agents and challenges with special emphasis on cyclooxygenase-2

B Kaur, P Singh - Bioorganic Chemistry, 2022 - Elsevier
corticosteroids to relieve associated swelling, pain and fever. … plasticity, oxidative stress,
autophagy, and apoptosis results … CV systems in comparison to indomethacin and diclofenac. …

[HTML][HTML] Protective effects of luteolin on injury induced inflammation through reduction of tissue uric acid and pro-inflammatory cytokines in rats

S Lodhi, GP Vadnere, KD Patil, TP Patil - Journal of traditional and …, 2020 - Elsevier
… and corticosteroids are frequently used for the management of pain and inflammation in
acute gout. Indomethacin … Luteolin belongs to the flavone group of flavonoids and has C6-C3-C6

Anti-inflammatory and antioxidant activities of Gymnema Sylvestre extract rescue acute respiratory distress syndrome in rats via modulating the NF-κB/MAPK pathway

A Jangam, SK Tirunavalli, BM Adimoolam… - …, 2023 - Springer
… µg/mL), different fractions of indomethacin (50 and 100 µM) or … Then DCFDA assay was
performed using BD-Accuri ® C6 … Though corticosteroids play a prominent role in mitigating the …

Development of aldose reductase inhibitors for the treatment of inflammatory disorders and cancer: Current drug design strategies and future directions

H Sonowal, KV Ramana - Current Medicinal Chemistry, 2021 - ingentaconnect.com
… the role of oxidative stress in the hyperglycemia-mediated … , such as corticosteroids, which
prevent inflammation, are the … of the hydroxyl group at C5, C6, C7, and C8 significantly …

Design, Synthesis, and Evaluation of N-[Substituted Benzoylamino]-5-Ethyl-1, 2, 3, 6-Tetrahydropyridines as Potential Selective Cox-2 Inhibitors and Anticancer …

S Gedeon - 2023 - search.proquest.com
… Cell viability studies were also performed to ensure that any observed activity was not due
to cell death. There was no observed cell death by all SG analogs and the COX-2 inhibitor

Protective effects of estrogen via nanoparticle delivery to attenuate myelin loss and neuronal death after spinal cord injury

A Haque, KP Drasites, A Cox, M Capone… - Neurochemical …, 2021 - Springer
… delivery technique using methylprednisolone-loaded … Rat C6 astrocytelike cell line was
purchased from the BCRC (… Thus, reducing ROS and oxidative stress-mediated secondary injury …

Next-generation nanomaterials: advancing ocular anti-inflammatory drug therapy

J Wei, J Mu, Y Tang, D Qin, J Duan, A Wu - Journal of nanobiotechnology, 2023 - Springer
… -inflammatory medications, such as corticosteroids [5, 6] and … eye syndrome, mitigated
oxidative damage in human trabecular … (DCPS) inhibited proliferation and induced apoptosis of …

Anti-Inflammatory Therapeutics: Conventional Concepts and Future with Nanotechnology

M Bernela, P Kaushal, N Verma… - Recent Advances in …, 2023 - ingentaconnect.com
Corticosteroids act on inflammation by inhibiting the activity of … Indomethacin loaded dextran
stearate polymeric micelles … rubicin-induced liver dysfunction: Impact on oxidative stress and …

Dietary polyphenols for management of rheumatoid arthritis: Pharmacotherapy and novel delivery systems

S Maity, S Wairkar - Phytotherapy Research, 2022 - Wiley Online Library
… bone and cartilage damage in AIA rats associated with the inhibition of factors responsible
for … , and oxidative stress in AIA rats. Moreover, this combination induced apoptosis marker …

Radioprotectors, Radiomitigators, and Radiosensitizers

A Montoro, E Obrador, D Mistry, GI Forte, V Bravatà… - Radiobiology …, 2023 - Springer
… biomolecules against oxidative stress and radioinduced … proliferation and to avoid
radio-induced cell death [12]. In fact, … ability to reduce oxidative stress, scavenge free radicals, …