microRNA-181 serves as a dual-role regulator in the development of human cancers

T Rezaei, M Amini, ZS Hashemi, B Mansoori… - Free Radical Biology …, 2020 - Elsevier
miRNAs may serve as diagnostic and prognostic biomarkers or therapeutic targets in human
cancer gene therapy… the miRNA-181 family as the active miRNAs in human cancers and …

Regulation of DNA methylation machinery by epi-miRNAs in human cancer: emerging new targets in cancer therapy

MR Karimzadeh, P Pourdavoud, N Ehtesham… - … Gene Therapy, 2021 - nature.com
targets for cancer therapy. In this review, at first, we have an overview of the methylation
alteration in cancers, and the effect of this phenomenon in miRNAs … epi-miRNAs in cancer cells. …

Molecular biomarkers in cancer

VK Sarhadi, G Armengol - Biomolecules, 2022 - mdpi.com
… Interestingly, the CRISPR/Cas13a system integrated into microfluidic chips with biosensors
has been successful in detecting miRNA biomarkers in serum samples of brain cancer

Urinary MicroRNAs as biomarkers of urological cancers: a systematic review

A Aveta, S Cilio, R Contieri, G Spena… - International Journal of …, 2023 - mdpi.com
… diagnostic biomarkers of urothelial carcinoma and bladder cancer (… UmiRNAs could serve
as therapeutic targets or recurrence … In renal cell carcinoma, miRNAs have been identified as …

Biomarkers in colorectal cancer: current research and future prospects

OO Ogunwobi, F Mahmood, A Akingboye - International journal of …, 2020 - mdpi.com
… purposes if combined with other microRNAs or other forms of biomarker. However, much of
… in use as a biomarker for risk of disease progression, survival, and as a therapeutic target. …

Exosomal miRNAs as biomarkers for diagnostic and prognostic in lung cancer

J Wu, Z Shen - Cancer medicine, 2020 - Wiley Online Library
… in cancer cells are related to tumorigenesis, 27 and … miRNAs biomarkers play an important
role in many cancers, such as nasopharyngeal carcinoma, lung cancer, and colorectal cancer

Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke

J Montaner, L Ramiro, A Simats, S Tiedt… - Nature Reviews …, 2020 - nature.com
… in gene expression and in expression of microRNAs (miRNAs) and long non-coding RNAs
(lncRNAs) have potential as stroke biomarkers. They also provide novel insight into the …

Drug resistance in osteosarcoma: emerging biomarkers, therapeutic targets and treatment strategies

CM Hattinger, MP Patrizio, L Fantoni, C Casotti… - Cancers, 2021 - mdpi.com
… has indicated miRNAs as candidate predictive biomarkers of poor drug response, with the
possibility to be taken into consideration also as therapeutic targets to reverse drug resistance…

MicroRNA as an important target for anticancer drug development

Z Fu, L Wang, S Li, F Chen, KKW Au-Yeung… - Frontiers in …, 2021 - frontiersin.org
… Furthermore, miRNA-based drugs target molecules that cannot be target molecules that …
cancer (Yu et al., 2020). Therefore, as drug targets, multi-target regulatory molecular miRNA has …

A comprehensive overview of circRNAs: emerging biomarkers and potential therapeutics in gynecological cancers

Y Ma, L Zheng, Y Gao, W Zhang, Q Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
… a potential therapeutic target in gynecological cancers and … can competitively combine with
related miRNAs to promote the … may be promising biomarkers and therapeutic targets for the …