… Exogenous insulin therapy is the primary approach for treating diabetes, especially T1DM, …
Insulin-loaded nanoparticles have recently attracted considerable interest because they can …

… approach involves the use of nanoparticle-based formulations like liposomes and polymeric
nanoparticles which can able to protect the insulin … The targeted delivery systems like micro …

… In this review, new approaches to oral insulin delivery for diabetes treatment are discussed,
including polymeric, lipid-based, and inorganic nanoparticles, as well as the clinical trials …

… advantages over the micro- or … nanoparticles because it is biocompatible and biodegradable
[16]. It is expected that the hydrophobic polymer, PLGA, will release hydrophilic insulin after …

… Barriers to oral insulin delivery along with suitable approaches reviewed … of insulin is around
5808 Da. In the majority of animals, there is only one insulin gene and one insulin protein [5…

… Based on articles published to date, we review the recent advances on INS micro- and
nanoencapsulation using only the unique properties of natural polysaccharides, including …

… with insulin in the absence of PLGA nanoparticles had the … loading insulin into PLGA based
nanoparticles protected insulin … nanoparticles based formulations is an applicable approach …

… for insulin therapy. To overcome poor bioavailability and the barriers to oral insulin absorption,
novel approaches in … Mucopenetrating insulin-loaded nanoparticles demonstrated a faster …

… , the utilization of multifunctional polymers, and micro-/nano particulate drug delivery systems
… on the use of nanoparticles (NPs) as carrier for peroral insulin delivery. This method has …

… of nano/micro-particles (eg, polymeric nanoparticles, liposomes, … approaches as previously
reported and the reliable insulin … and synthesized insulin-encapsulated nanoparticles (DNPs) …