Experimental Models in Parkinson's Disease: Advantages and Disadvantages
… While 6-OHDA cannot mimic all aspects of the disease, it appears to be a replica of PD in
humans. … However, some drawbacks of using rotenone in PD modeling include the lack of well-…
humans. … However, some drawbacks of using rotenone in PD modeling include the lack of well-…
[HTML][HTML] Is activation of GDNF/RET signaling the answer for successful treatment of Parkinson's disease? A discussion of data from the culture dish to the clinic
JA Conway, ER Kramer - Neural Regeneration Research, 2022 - journals.lww.com
… Parkinson's disease patients, which mainly focused on optimizing the GDNF delivery technique,
benefits … It is speculated that BT13 mimics soluble GDNF/GFRα1, rather than GDNF itself…
benefits … It is speculated that BT13 mimics soluble GDNF/GFRα1, rather than GDNF itself…
[HTML][HTML] Cell models for Alzheimer's and Parkinson's disease: At the interface of biology and drug discovery
… information about the therapeutic benefits of drugs under development. … This hallmark is
used in the development of models that mimic the … The major pros and cons of cell models in …
used in the development of models that mimic the … The major pros and cons of cell models in …
[图书][B] Rethinking Parkinson's Disease: The definitive guide to the known causes of Parkinson's disease and proven reversal strategies
JC Coleman - 2020 - books.google.com
… dish with a particular mould were dead. Instead of ignoring … Advantages of Western allopathic
medicine treatment for … effects mimicking one or more symptoms of Parkinson’s disease. …
medicine treatment for … effects mimicking one or more symptoms of Parkinson’s disease. …
[HTML][HTML] Microglia in a dish—which techniques are on the menu for functional studies?
P Aktories, P Petry, K Kierdorf - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
… models is wide and they come with different advantages and … organotypic environment by
mimicking direct interactions … specific neurological disorder like Parkinson’s disease and then …
mimicking direct interactions … specific neurological disorder like Parkinson’s disease and then …
[HTML][HTML] Current state-of-the-art and unresolved problems in using human induced pluripotent stem cell-derived dopamine neurons for parkinson's disease drug …
SA Antonov, EV Novosadova - International Journal of Molecular …, 2021 - mdpi.com
… The introduction of 3D culture methods to mimic the brain … However, while the benefits for
basic and applied studies … the floor plate genes is apparently the most widely used method for …
basic and applied studies … the floor plate genes is apparently the most widely used method for …
[HTML][HTML] In vitro Models of Neurodegenerative Diseases
A Slanzi, G Iannoto, B Rossi, E Zenaro… - Frontiers in cell and …, 2020 - frontiersin.org
… , mimicking neuronal and glial cell interactions, and incorporating the effects of blood flow. In
this review, we discuss the relative merits of … bioreactor with a microtiter plate format. Within …
this review, we discuss the relative merits of … bioreactor with a microtiter plate format. Within …
[HTML][HTML] A critical review of zebrafish models of Parkinson's disease
… The end goal of this review is to determine the benefits of using zebrafish in comparison to
utilising … No animal model can perfectly mimic human disease, especially highly complex …
utilising … No animal model can perfectly mimic human disease, especially highly complex …
Clinical and Imaging Pitfalls in the Diagnosis of Idiopathic Parkinson's Disease 237
A Chakravarty - … in the Diagnosis of Neurological Disorders, 2022 - books.google.com
… used commonly, is somewhat controversial. While some authors have suggested that different
disorders mimicking … and metabolic disorders may cause tremors which merit mentioning. …
disorders mimicking … and metabolic disorders may cause tremors which merit mentioning. …
[HTML][HTML] Comprehensive perspectives on experimental models for Parkinson's disease
… Pigs have the advantages for mimicking human disease due to their unique features
exhibiting not only high homology of human genes but also similarities in anatomy, metabolism, …
exhibiting not only high homology of human genes but also similarities in anatomy, metabolism, …