[HTML][HTML] Neuroprotective effects of doxycycline in the R6/2 mouse model of Huntington's disease

E Paldino, C Balducci, P La Vitola, L Artioli… - Molecular …, 2020 - Springer
… ), the administration of minocycline was associated with the delay of disease progression.
In … huntingtin by minocycline and doxycycline was not associated with beneficial effects in …

Minocycline and doxycycline: more than antibiotics

S Singh, D Khanna, S Kalra - Current Molecular Pharmacology, 2021 - ingentaconnect.com
… and pyruvate treatment reversed the neuronal insult produced by striatal injection of
quinolinic acid, an excito-toxic animal model of Huntington's disease. Inflammatory responses …

Repurposing of Minocycline, a Tetracycline Antibiotic, for Neurodegenerative Disorders

RB Sanshita, P Sood, D Thakur, A Kuhad - … Emerging Infectious Diseases …, 2023 - Springer
… Alzheimer’s disease, Huntington's disease, Parkinson’s disease, Amyotrophic lateral …
effect of minocycline in several models of acute and chronic neurodegenerative disease like …

Challenges of repurposing tetracyclines for the treatment of Alzheimer's and Parkinson's disease

I Markulin, M Matasin, VE Turk… - Journal of Neural …, 2022 - Springer
… The research in animal AD/PD models provided evidence on … The neuroprotective effects
of minocycline and doxycycline … a long-standing doxycycline and minocycline therapy in these …

The mechanisms underlying minocycline non-antibiotic effects

GJA Fernandes - 2022 - repositorio.ul.pt
… This effect has been confirmed in experimental models of … including Parkinson's disease,
Huntington's disease, amyotrophic … as antibiotics are doxycycline and minocycline, which are …

[HTML][HTML] The potential use of tetracyclines in neurodegenerative diseases and the role of nano-based drug delivery systems

M Rahmani, SEN Álvarez, EB Hernández - European Journal of …, 2022 - Elsevier
… neuroprotective roles of minocycline and doxycycline in four … neurodegenerative disorders
(ALS, Huntington's disease, PD… In most CNS models the dose of minocycline required to …

Minocycline in neurological disorders treatment

CQC Leite - 2021 - repositorio.ul.pt
… , with doxycycline taking its place and minocycline being currently … diseases and rheumatoid
arthritis. Among tetracyclines, … In an EAE animal model, minocycline reduced Tumor …

Tetracyclines for Prevention and Treatment of Nervous System Disorders

CAG Rocha - 2020 - search.proquest.com
… absorption of minocycline and doxycycline does not appear … (12), although, oral doxycycline
and minocycline must be taken … pathways in models of Huntington's disease. Proceedings of …

Metalloproteinases and their inhibitors in neurological disease

ER Lopez-Navarro, J Gutierrez - Naunyn-Schmiedeberg's Archives of …, 2022 - Springer
minocycline or doxycycline, no … ) not on antiretrovirals to test whether minocycline had an
effect on neurocognitive performance. In this study, minocycline failed to demonstrate a benefit

[HTML][HTML] Immunotherapies in Huntington's disease and α-Synucleinopathies

O Fatoba, Y Ohtake, T Itokazu, T Yamashita - Frontiers in Immunology, 2020 - frontiersin.org
… signaling was shown to be beneficial in an HD rodent model (98). DN… models might be
warranted to validate etanercept efficacy. … Minocycline has been shown to be protective in several …