Neuroprotective effect of minocycline against acute brain injury in clinical practice: a systematic review

BA Strickland, J Bakhsheshian, B Emmanuel… - Journal of Clinical …, 2021 - Elsevier
… The objective of our search was to identify relevant studies concerning the utility of minocycline
as a neuroprotective agent in acute brain injury inclusive of TBI, cerebral ischemia, ICH, …

Neuroprotective effects of minocycline on focal cerebral ischemia injury: a systematic review

Y Naderi, Y Panahi, GE Barreto… - Neural regeneration …, 2020 - journals.lww.com
… The results of this review can help us recognize this drug as a neuroprotective agent for the
improvement of neurological dysfunction following stroke. Thrombolytic agents such as tPA …

[HTML][HTML] Minocycline and magnesium as neuroprotective agents for ischemic stroke: a systematic review

JF Ortiz, S Ruxmohan, A Saxena, ÁM Cox, F Bashir… - Cureus, 2020 - ncbi.nlm.nih.gov
… We found five clinical trials of minocycline for the treatment of ischemic stroke. The oldest
article was conducted in 2007, and the latest article was published in 2014. The clinical trials …

Minocycline as a neuroprotective agent in arsenic-induced neurotoxicity in PC12 cells

M Shayan, S Mehri, BM Razavi… - Biological Trace Element …, 2023 - Springer
… effect of minocycline, a widely used antimicrobial agent with … Cells were pre-treated with
minocycline (50 nM–1 µM) for 2 h, … Minocycline not only attenuated arsenic-induced cytotoxicity …

Minocycline in neurodegenerative and psychiatric diseases: an update

D Romero‐Miguel, N Lamanna‐Rama… - European Journal of …, 2021 - Wiley Online Library
… as a microglia inhibitor and anti-inflammatory agent, minocycline was therefore indicated
to … In different rodent models, minocycline proved to be effective as a neuroprotective agent

[HTML][HTML] Minocycline Acts as a Neuroprotective Agent Against Tramadol-Induced Neurodegeneration: Behavioral and Molecular Evidence

M Gholami, Z Ghelichkhani, R Aghakhani… - … Journal of Preventive …, 2024 - journals.lww.com
… as a neuroprotective agent, its … neuroprotective effects of MIN against TRA-induced
neurodegeneration. To better understand the mechanism behind the interaction of these two agents, …

EFFECTS OF MINOCYCLINE AS A NEUROPROTECTIVE AGENT FOR STROKE ON MMP-9 LEVELS, FUNCTIONAL OUTCOME, AND MORTALITY

AI Nisa, AA Damayanti, J Nagasastra… - Folia Medica …, 2024 - search.proquest.com
Minocycline has multiple mechanisms of action, including anti-inflammatory and anti-apoptotic,
which contribute to its appeal as a neuroprotective agent. Aside from that, minocycline

Evaluating Minocycline as a Neuroprotective Agent in an Aged Female Rat MCAO Stroke Model

L Gutierrez, VM Tutino, AH Siddiqui - bioRxiv, 2023 - biorxiv.org
… Using these two models, we evaluated the neuroprotective qualities of the antibiotic,
minocycline. We found that those in the treatment groups experienced a greater improvement in …

Minocycline and doxycycline: more than antibiotics

S Singh, D Khanna, S Kalra - Current Molecular Pharmacology, 2021 - ingentaconnect.com
… However, minocycline modulates neuroprotective effect of hesperidin and gave potentiated
effects against behavioral, biochemical, cellular and histological changes [157]. Li et al., (…

The possible role of CREB‐BDNF signaling pathway in neuroprotective effects of minocycline against alcohol‐induced neurodegeneration: molecular and behavioral …

M Motaghinejad, R Mashayekh… - Fundamental & …, 2021 - Wiley Online Library
… In animal models, the doses of minocyclineminocycline doses for neuroprotection [2, 23-32].
In this research, we attempted to provide insight into the neuroprotective role of minocycline