… was rapidly phosphorylated upon naïve T cell activation in … In the absence of mitogenic
signals, T cells do not require de … pyrimidine synthesis caused a post-transcriptional inhibition of …

… T-cells (NFAT), and activator protein 1 (AP-1) transcription … the rapid phosphorylation of
immunoreceptor tyrosine-based … subsequent exposure to antigen or mitogenic stimulation [41]. …

… the cell, which mediate the activation of various genes with the help of specific transcription
… negatively regulate LCK function by removing tyrosine phosphorylation from LCK-Y 394 . …

… , we found that the level of phosphorylation of CD3ζ, ZAP70, … engagement, as mitogens do
not stimulate T cells through the … : resting T cells, activated T cells, activated T cells cocultured …

… -dependent transcriptional output through phosphorylation-… ELK1 phosphorylation sites
that are rapidly phosphorylated … spikes of mitogen stimulation are required for cells arrested in …

… CD4 + T cells were reduced, while CD8 + T cells consisted … to mitogens as well as
diminished cytokine secretion. B-… The key event of p105 phosphorylation on ligand binding was …

… activator of transcription 3 (STAT3) of CD8+ T cells in obese … NF-κB phosphorylation and
activation, reduce CD8+ T cell … fusion by activating the p38- mitogen-activated protein kinase (…

… potential activation of MAPK by osmolarity, pH changes, or mitogen … phosphorylation, the
same sample but unsorted was suspended and stored in sorting buffer (Fig. 2C). Transcription …

… This quick transition from naïve T cells into effector T cells … -mTOR signalling, (b)
mitogen-activated protein kinase (MAPK) … influx and drives phosphorylation of NFAT transcription …

… are required for the transcriptional and metabolic changes … depend on glycolysis, oxidative
phosphorylation (OXPHOS), … Mitogen-activated thymocytes [33] and peripheral T cells [34] …