… tools and strategies of systems metabolic engineering, including in silico genome-scale
metabolic simulation, sophisticated enzyme engineering, … , and genomic engineering, employed …

… Recent advances in synthetic biology and systems biology have provided the tools for
dynamic metabolic engineering while control theory has provided new design principles for …

… unique opportunity to make metabolic engineering more predictable. In this review, we offer
an introduction to this discipline in terms that are relatable to metabolic engineers, as well as …

… are central concepts in metabolic engineering, as was emphasized in the first paper published
in this journal, “Metabolic fluxes and metabolic engineering” (Metabolic Engineering, 1: 1–…

… Metabolic engineering is nowadays on track towards a truly … metabolic pathways in engineered
producer strains. In this review, we discuss how the success of the metabolic engineering …

… Here, we review the latest attempts of combining systems biology and AI in metabolic
engineering research, and highlight how this alliance … combining different sub-model simulations. …

… A special aim of this book is to demonstrate that you do not have to be an engineer to
learn modeling and simulation. The basic concepts of the material balance, combined with …

… and tools used in metabolic engineering with a focus on the DBTL cycle in the model organisms
E. coli … Then, we highlight some representative applications of metabolic engineering for …

… In the coming sections, we discuss various tools that apply FBA to predict the metabolic …
the metabolic fluxes and non-steady-state conditions [31]. Below, we review high-quality models …

… experimental tools and models available for metabolic engineering. 1.3 Computational
modelling … In chapter 2 I review model-driven metabolic engineering, consolidating the lessons I …