Evidence for early dispersal of domestic sheep into Central Asia

WTT Taylor, M Pruvost, C Posth, W Rendu… - Nature Human …, 2021 - nature.com
… number of these anthropogenically modified specimens were … We next compared genome-wide
sequences of the Obishir V … connections and domestic animal dispersals. Although our …

[HTML][HTML] Genetically modified rabbits for cardiovascular research

J Fan, Y Wang, YE Chen - Frontiers in genetics, 2021 - frontiersin.org
animal staff, it is necessary to make genetically modified rabbits … stem (ES) cells and the
genome information, it has been … recombination-based genomic modification as to generate KO …

[HTML][HTML] Organoids in domestic animals: with which stem cells?

B Pain - Veterinary Research, 2021 - Springer
… The possibility of deriving reprogrammed human-induced PSCs (hiPSCs) from patient
biopsies, modifying them, and obtaining isogenic cells by reversing mutations through genome

[HTML][HTML] Genomic analysis, progress and future perspectives in dairy cattle selection: a review

MA Gutierrez-Reinoso, PM Aponte, M Garcia-Herreros - Animals, 2021 - mdpi.com
… specific genetic modifications that can be applied to virtually any organism was discovered,
and a year later, it was successfully applied to make specific modifications in the genome of …

Mechanisms by which mastitis affects reproduction in dairy cow: A review

N Wang, C Zhou, W Basang, Y Zhu… - … in Domestic Animals, 2021 - Wiley Online Library
genomic analysis, epigenetic modification, microbiota, inflammatory regulation and immune
evasion mechanism of mastitis, aiming to provide directions for the prevention and control of …

[HTML][HTML] Insights into the roles of sperm in animal cloning

P Qu, Y Wang, C Zhang, E Liu - Stem Cell Research & Therapy, 2020 - Springer
modification, DNA methylation, genomic imprinting, and noncoding RNA regulation are
the main forms of epigenetics. The original epigenetic modifications in donor cell genome are …

[HTML][HTML] Brucella Genomics: Macro and Micro Evolution

M Suárez-Esquivel, E Chaves-Olarte, E Moreno… - International journal of …, 2020 - mdpi.com
… wild animals. These changes are linked to modifications in the genetic flow of domesticated
… isolates from wildlife and domestic animals are lacking. One important exception is B. ovis. …

Establishment of bovine expanded potential stem cells

L Zhao, X Gao, Y Zheng, Z Wang… - Proceedings of the …, 2021 - National Acad Sciences
… We modified the pEPSCM and developed bEPSCM for … modifications in the bovine genome.
We next explored using … for producing animals with sophisticated genetic modifications. …

The CRISPR/Cas9 induces large genomic fragment deletions of MSTN and phenotypic changes in sheep

D Yi, SW Zhou, D Qiang, CAI Bei, XE Zhao… - Journal of Integrative …, 2020 - Elsevier
… This enabled significant progress in the generation of genetically edited animals. The most
recent CRISPR/Cas9 system is an efficient tool for the genomic modification of targeted loci …

The coding loci of evolution and domestication: current knowledge and implications for bio-inspired genome editing

V Courtier-Orgogozo, A Martin - Journal of Experimental …, 2020 - journals.biologists.com
… has mostly focused on artificial targeted modifications of genes (via gene inactivation or … in
a farm animal illustrates how our knowledge of existing variants can inform or inspire genome