Novel insights regarding nitric oxide and cardiovascular diseases

T Infante, D Costa, C Napoli - Angiology, 2021 - journals.sagepub.com
… ) is a powerful mediator with biological activities such as vasodilation and … modulation
of NO-cGMP signaling pathway was also investigated for a possible therapeutic approach

Nitric oxide: physiological functions, delivery, and biomedical applications

SM Andrabi, NS Sharma, A Karan… - Advanced …, 2023 - Wiley Online Library
… advancing treatment strategies for various medical problems. … bioactivity of NO by reducing
the diffusion efficiency of NO (… by angiotensin II which modulates mitochondrial NOS.[106] …

Nitrate-functionalized patch confers cardioprotection and improves heart repair after myocardial infarction via local nitric oxide delivery

D Zhu, J Hou, M Qian, D Jin, T Hao, Y Pan… - Nature …, 2021 - nature.com
… been ascribed to the bioactive molecule nitric oxide, which is … development of innovative
therapeutic strategies for MI, including … patches modulated macrophage polarization into the M2 …

Polymeric nitric oxide delivery nanoplatforms for treating cancer, cardiovascular diseases, and infection

G Jin, Z Gao, Y Liu, J Zhao, H Ou… - Advanced Healthcare …, 2021 - Wiley Online Library
… A), a key player in the modulation of biofilm formation and dispersal. Once … [ 116 ] NO has the
biological activities of which include … need to develop alternative treatment strategies. [ 154 ] …

Nitric oxide-producing cardiovascular stent coatings for prevention of thrombosis and restenosis

J Rao, H Pan Bei, Y Yang, Y Liu, H Lin… - … in bioengineering and …, 2020 - frontiersin.org
… Since NOS has emerged as an active player in NO generation, a lot of therapeutic strategies
have been developed around it. Gene therapy in CVDs can improve the selectivity of …

Nitric oxide as a central molecule in hypertension: Focus on the vasorelaxant activity of new nitric oxide donors

GM da Silva, MC da Silva, DVG Nascimento… - Biology, 2021 - mdpi.com
… capable of releasing NO in a modulated and stable way. … remain intact after cardiac
surgery, consumption reaction … oxidative stress and impairment in nitric oxide bioactivity [196]. …

Nitric oxide-cGMP signaling in hypertension: current and future options for pharmacotherapy

E Ataei Ataabadi, K Golshiri, A Jüttner, G Krenning… - …, 2020 - Am Heart Assoc
… Second, it increases natriuresis through modulation of various … Decrease of bioactive NO
by superoxide occurs under the … , there are currently no pharmacological strategies to target …

Current advances of nitric oxide in cancer and anticancer therapeutics

J Mintz, A Vedenko, O Rosete, K Shah, G Goldstein… - Vaccines, 2021 - mdpi.com
… into a variety of bioactive nitrogen oxides. This reduction is … investigated as a potential
autologous therapy approach [90,91]… been shown to modulate nitric oxide expression, through the …

[HTML][HTML] Nitric oxide-releasing biomaterials for promoting wound healing in impaired diabetic wounds: State of the art and recent trends

R Ahmed, R Augustine, M Chaudhry, UA Akhtar… - Biomedicine & …, 2022 - Elsevier
… Currently, treatment strategiesNO for the treatment of a specific disease. Thus, a specific
relationship exists between biological processes and NO concentration in a biological activity

[HTML][HTML] Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries

T Zhao, W Wu, L Sui, Q Huang, Y Nan, J Liu, K Ai - Bioactive Materials, 2022 - Elsevier
… to identify therapeutic strategies for reducing the infarct size and severity [8]. Excessive ROS
can damage cardiac muscle … The modulation of NOX activity is particularly attractive for …