Sulforaphane: A review of its therapeutic potentials, advances in its nanodelivery, recent patents, and clinical trials
… SFN exerted its anticancer efficacy by modulating the key … revealed that SFN exhibited
cardioprotective effects against post-… due to phase I and phase II drug metabolism enzymes (DME…
cardioprotective effects against post-… due to phase I and phase II drug metabolism enzymes (DME…
Protective effects of sulforaphane on type 2 diabetes-induced cardiomyopathy via AMPK-mediated activation of lipid metabolic pathways and NRF2 function
Y Sun, S Zhou, H Guo, J Zhang, T Ma, Y Zheng… - Metabolism, 2020 - Elsevier
… enzyme comprised of one catalytic subunit (α1 or α2) and … The SFN-mediated
cardioprotective effects, which is … than α1 in modulating mitochondria function, as its potential in …
cardioprotective effects, which is … than α1 in modulating mitochondria function, as its potential in …
Sulforaphane effects on cardiac function and calcium-handling–related proteins in 2 experimental models of heart disease: ischemia-reperfusion and infarction
JHP Bonetto, AL de Castro, RO Fernandes… - Journal of …, 2022 - journals.lww.com
… Cardioprotective role of sulforaphane (SFN), a natural … increased expression of phase
II and antioxidant enzymes. SFN … study was that SFN administration modulates calcium-handling …
II and antioxidant enzymes. SFN … study was that SFN administration modulates calcium-handling …
[PDF][PDF] The Emergence of Sulforaphane as a Clinically-Relevant Nutraceutical in the Prevention and Treatment of Disease
CA Houghton - Current Topics in Medicine and Medical Research, 2020 - researchgate.net
… as such has the potential to modulate the expression of genes … Thioredoxin is implicated in
cardioprotection by triggering … Oral sulforaphane increases Phase II antioxidant enzymes in …
cardioprotection by triggering … Oral sulforaphane increases Phase II antioxidant enzymes in …
Sulforaphane as an anticancer molecule: Mechanisms of action, synergistic effects, enhancement of drug safety, and delivery systems
… Sulforaphane also modulates Phase II enzymes through … effect of sulforaphane with GEM
on clonogenic potential of CSC … Similar cardioprotective effect of sulforaphane against DOX …
on clonogenic potential of CSC … Similar cardioprotective effect of sulforaphane against DOX …
Anticancer properties of sulforaphane: current insights at the molecular level
M Asif Ali, N Khan, N Kaleem, W Ahmad… - Frontiers in …, 2023 - frontiersin.org
… The epigenetic modulation of sulforaphane on breast cancer … To study the effect of
sulforaphane, a randomized control trial … Sulforaphane-stimulated phase ii enzyme induction …
sulforaphane, a randomized control trial … Sulforaphane-stimulated phase ii enzyme induction …
Sulforaphane prevents age‐associated cardiac and muscular dysfunction through Nrf2 signaling
… for muscle myostatin, a negative modulator of SKM mass (… a diet containing SFN is
cardioprotective and enhances exercise … by enhancing phase 2 detoxification and antioxidant …
cardioprotective and enhances exercise … by enhancing phase 2 detoxification and antioxidant …
Sulforaphane, an Nrf-2 agonist, modulates oxidative stress and inflammation in a rat model of cuprizone-induced cardiotoxicity and hepatotoxicity
G Ibrahim Fouad - Cardiovascular Toxicology, 2023 - Springer
… The main target of this study is to evaluate the cardioprotective and … Effect of CPZ
administration and SF treatment on … the genetic expression of phase II detoxification enzymes [83]. …
administration and SF treatment on … the genetic expression of phase II detoxification enzymes [83]. …
Essential role of Nrf2 in sulforaphane-induced protection against angiotensin II-induced aortic injury
H Wang, Y Tian, Q Zhang, W Liu, L Meng, X Jiang… - Life Sciences, 2022 - Elsevier
… to explore the potential of SFN in protecting against Ang II-… effect by inhibiting AT1
expression and NOX enzyme activation… genes and phase II detoxification enzymes to maintain …
expression and NOX enzyme activation… genes and phase II detoxification enzymes to maintain …
Sulforaphane—a compound with potential health benefits for disease prevention and treatment: insights from pharmacological and toxicological experimental studies
… in numerous tissues by activating phase II enzymes and, subsequently, by … cardioprotective
effect by reducing the expression of the ryanodine receptor (Ryr), leading to modulation …
effect by reducing the expression of the ryanodine receptor (Ryr), leading to modulation …