… virulence factors that contribute to fungal intracellular survival. … confirmed that live fungus
was required to modulate the … The effect of replicative aging on phagosomal maturation in …

… CR can influence the replicative lifespan (RLS) of various organisms by modulating several
… and greater virulence of MATα cells. Our data further encourage efforts to characterize …

… To investigate the effects of replicative aging on gene … backgrounds and examines the effect
of MitoTEMPO treatment … respiration is crucial for cryptococcal virulence, in vivo resilience, …

… IMPORTANCE Cryptococcus neoformans and Candida … drugs (10) because it is essential
for fungal virulence (11). This study … to elucidate the implications of EV secretion during aging, …

… glabrata, and Cryptococcus neoformans are pathogenic yeasts … The studies indicate that
aging is relevant for virulence in … effect on life span that was observed by chemical modulation …

… that replicative aging conveys enhanced resilience within the host environment. 78 … To
investigate the effects of replicative aging on gene expression in Cn, we performed 94 …

… gattii exhibited cell wall damage and reduced virulence, whereas Cda1 defects had no
effect on the … [65], and Hsp70 was recently proved to modulate the interaction between C. …

… the interplay between virulence factor expression and QS, as well as the effect NL has on …
neoformans is also modulated in response to local nitrogen concentrations. When grown in …

… this homologue gene seems to be redundant with no effect on the virulence of serotype A [29].
… , and DNA replication (by modulating the activity of Orc2p while initiating DNA replication). …

… cryptococcal virulence factor (12, 13). The various serotypes result in prominent differences
in both pathology and immune modulation … implications to how macrophages interact with C. …