… inhibition of hdc or exposure to α-fluoromethylhistidine leads to decreased numbers of hypocretin
… to understand the full range of physiological functions of zebrafish histamine receptors. …

… Based on evidence that histamine has a role in neurogenesis and on the literature … an
important modulator in this process [3], we aimed to verify the effects of hrh1 deletion on zebrafish …

… Indeed, due to easily differentiable behavioral patterns and the … animals, zebrafish have
become a convenient platform to study candidate neurotropic drugs [19]. Zebrafish histaminergic …

… acid, acetylcholine, and histamine signaling pathways in zebrafish brains at the H treatments.
The … of the zebrafish brain, neurotransmitters, and associated fish behaviors and may help …

… Histamine receptors play pivotal roles in various physiological functions, ranging from … fish
behavior. Thus, cetirizine demonstrated the least impact on the central nervous system among …

… After administration of α-FMH (α-fluoromethylhistidine, an irreversible and … Histamine system
is strongly suggested to play an essential role in modulating sleep and wake behavior via H …

… histamine leads to upregulation of the dopaminergic system in the striatum, which in turn
leads to altered behavioral … of this differential modulation of neuronal activity by histamine and …

… For example, administration of α-fluoromethylhistidine, which is an inhibitor of HDC, results
… fact that drugs targeting the central histaminergic system can modulate the level of arousal as …

… The mRNA level of the rate-limiting enzyme in histamine synthesis, histidine decarboxylase,
… -type zebrafish that we challenged in the social hierarchy test and studied the behaviors of …

… For the second aim, the study injected α-fluoromethylhistidine (α-FMH) into the ventricle of
… of α-FMH to compare the size of the striatum and proliferative zones between control and α-…