[HTML][HTML] Role of oxidative damage in alzheimer's disease and neurodegeneration: From pathogenic mechanisms to biomarker discovery

FR Buccellato, M D'Anca, C Fenoglio, E Scarpini… - Antioxidants, 2021 - mdpi.com
… in the progression of the disease. This review will focus on oxidative damage products as
possible peripheral biomarkers in AD and in the preclinical phases of the disease. Particular …

[HTML][HTML] Oxidative stress and mitochondrial damage in neurodegenerative diseases: from molecular mechanisms to targeted therapies

G Cenini, A Lloret, R Cascella - Oxidative Medicine and Cellular …, 2020 - ncbi.nlm.nih.gov
… Thus, it is not surprising that oxidative stress, as well as alterations in brain energy … of several
neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD)…

[HTML][HTML] Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer's disease

T Guo, D Zhang, Y Zeng, TY Huang, H Xu… - Molecular …, 2020 - Springer
… Although we have gained much towards understanding various aspects underlying … research
in molecular mechanism, diagnostics and treatment will be needed in future AD research. …

Mitochondria and cellular redox state on the route from ageing to Alzheimer's disease

G Abate, M Vezzoli, M Sandri… - Mechanisms of Ageing …, 2020 - Elsevier
… Among several age-related diseases, mitochondrial dysfunction and oxidative stress were
intimately linked with progression to Alzheimer’s disease (AD), the most prevalent form of …

Oxidative stress: The core pathogenesis and mechanism of Alzheimer's disease

R Bai, J Guo, XY Ye, Y Xie, T Xie - Ageing research reviews, 2022 - Elsevier
… Taking oxidative stress as the central point, this review comprehensively expands on the
roles of oxidative stress … In vivo oxidative stress in brain of Alzheimer disease transgenic mice: …

Role of mitochondrial dysfunction, oxidative stress and autophagy in progression of Alzheimer's disease

V Bhatia, S Sharma - Journal of the neurological sciences, 2021 - Elsevier
Oxidative stress animbalance between the oxidants and antioxidants … diseases such as AD
and Huntington's disease(HD) [45]. The current review summarizes the role of oxidative stress

[HTML][HTML] The link between oxidative stress, mitochondrial dysfunction and neuroinflammation in the pathophysiology of Alzheimer's disease: Therapeutic implications …

MC Jurcău, FL Andronie-Cioara, A Jurcău, F Marcu… - Antioxidants, 2022 - mdpi.com
… Although oxidative stress has many sources and interferes with many pathways, to keep the
… complex relationships between oxidative stress, mitochondrial dysfunction, cellular protein …

[HTML][HTML] Mitochondrial dysfunction and oxidative stress in Alzheimer's disease

A Misrani, S Tabassum, L Yang - Frontiers in aging neuroscience, 2021 - frontiersin.org
… Several lines of evidence indicate that oxidative and nitrosative stress can lead to changes
in vital cellular elements such as nucleic acids, lipids, and proteins. ROS comprise of both …

RNA and oxidative stress in Alzheimer's disease: focus on microRNAs

A Nunomura, G Perry - Oxidative medicine and cellular …, 2020 - Wiley Online Library
Oxidative stress (OS) is considered as one of the major underlying mechanisms of AD and
related neurodegenerative disorders. Indeed, oxidative damage is closely associated with …

mTOR in Alzheimer disease and its earlier stages: Links to oxidative damage in the progression of this dementing disorder

M Perluigi, F Di Domenico, E Barone… - Free Radical Biology and …, 2021 - Elsevier
… plaques indicates a close association between oxidative damage and AD lesions [38]. Indeed,
the brains of patients with MCI and AD also have increased oxidative alterations, such as …