Thyroid Neuroendocrine Neoplasms

SL Asa, O Mete - The Spectrum of Neuroendocrine Neoplasia: A …, 2021 - Springer
… parathyroid tumors, NENs originating from intrathyroidal thymic remnants and metastatic
neuroendocrine neoplasms. … of the molecule in the extracellular and transmembrane domain, all …

Neuroendocrine neoplasms: Historical background and terminologies

SL Asa, RV Lloyd, AS Tischler - The spectrum of neuroendocrine …, 2021 - Springer
… The use of immunohistochemistry allows pathologists to apply more sophisticated
biomarkers to facilitate the molecular histopathologic classification of endocrine tumors. The …

Immunohistochemistry in the diagnosis and classification of neuroendocrine neoplasms: what can brown do for you?

AM Bellizzi - Human pathology, 2020 - Elsevier
… markers in NEC; Rb inactivation, a molecular genetic hallmark of small cell lung cancer, is a
… of lung NENs, contained in the WHO Classification of Tumours of the Lung, Pleura, Thymus, …

Neuroendocrine Tumors (Thymic and Gastroenteropancreatic): Anatomy, Endocrine Physiology, and Pathophysiology

MJ Stechman, R Bränström - Endocrine Surgery Comprehensive Board …, 2022 - Springer
… The management of patients with neuroendocrine tumors (NETs) is often complex due to their
… The most recent WHO classification for gastrointestinal neuroendocrine tumors dates from …

Clinical implications of lung neuroendocrine neoplasm classification

J Metovic, M Barella, S Harari, L Pattini… - Expert Review of …, 2021 - Taylor & Francis
… lung NENs in terms of biological behavior and molecular traits. This is particularly true in the
… Interestingly, this model can even be documented in a variety of non-neuroendocrine tumors

[HTML][HTML] Thymic epithelial tumors: An evolving field

E Kuhn, C Pescia, P Mendogni, M Nosotti, S Ferrero - Life, 2023 - mdpi.com
… thymoma, thymic carcinoma, and thymic neuroendocrine neoplasms. Characteristically, …
Of note, the molecular landscape of thymic carcinoma alone is profoundly heterogeneous, …

[HTML][HTML] Molecular classification of extrapulmonary neuroendocrine carcinomas with emphasis on POU2F3-positive tuft cell carcinoma

J Koh, H Kim, KC Moon, C Lee, K Lee… - The American Journal …, 2023 - journals.lww.com
Neuroendocrine carcinoma (NEC) is a rare malignancy with poor prognosis. … the thymic
origin tumors among EP-NEC/PDCs expressed POU2F3. In our patients, thymic epithelial tumors

Current understanding of pathogenetic mechanisms in neuroendocrine neoplasms

R Modica, A Liccardi, R Minotta… - Expert Review of …, 2024 - Taylor & Francis
… 25% of patients with thymic carcinoid tumors harbor a MEN1 germline mutation and 8%
of MEN1 patients develop T-NENs [Citation129,Citation130]. The molecular evaluation of T-…

[HTML][HTML] Biomarker landscape in neuroendocrine tumors with high-grade features: current knowledge and future perspective

M Prisciandaro, M Antista, A Raimondi, F Corti… - Frontiers in …, 2022 - frontiersin.org
… performed, a molecular classification of NET is … thymus NEN), and 10% of the primary tumor
remains unknown (2–4). According to the 2019 WHO classification, GEP NENs are classified

[HTML][HTML] Molecular factors, diagnosis and management of gastrointestinal tract neuroendocrine tumors: An update

ET Pavlidis, TE Pavlidis - World Journal of Clinical Cases, 2022 - ncbi.nlm.nih.gov
… features, histopathologic classification, diagnosis and … Neuroendocrine carcinoma of the
gastrointestinal system is … distinct from gastrointestinal system neuroendocrine tumors (NETs). …