Glaucoma, the world's leading cause of irreversible blindness, is a complex disease, with
differential presentation as well as ethnic and geographic disparities. The multifactorial
nature of glaucoma complicates the study of genetics and genetic involvement in the
disease process. This review synthesizes the current literature on glaucoma and genetics,
as stratified by glaucoma subtype and ethnicity. Primary open-angle glaucoma (POAG) is
the most common cause of glaucoma worldwide, with the only treatable risk factor (RF) …

Glaucoma, the world's leading cause of irreversible blindness, is a complex disease, with
differential presentation as well as ethnic and geographic disparities. The multifactorial
nature of glaucoma complicates the study of genetics and genetic involvement in the
disease process. This review synthesizes the current literature on glaucoma and genetics,
as stratified by glaucoma subtype and ethnicity. Primary open-angle glaucoma (POAG) is
the most common cause of glaucoma worldwide, with the only treatable risk factor (RF) …