… In summary, pancreatic cancer remains a disease with poor long-… pancreatic cancer
treatment and the milestones that brought us to where we are today, along with emerging therapies…

… the pancreatic head, suspicious for a small insulinoma, but endoscopic ultrasound failed to
localize the tumor… any abnormal uptake concerning for neuroendocrine tumor, and a selective …

… tumor survival [79]. Clarifying the impact of the dynamic CAF environment on tumor growth
and metastasis may inform novel treatment strategies targeting specific CAF populations. …

… combinatorial therapies with CDK4/6i’s. Table 1 shows mutated genes in mCRPC and
will be referred throughout this review in guiding novel combinatorial therapeutic strategies. …

… cancer. These studies support DRD2 antagonism via ONC201 as a promising therapeutic
strategy for endometrial cancer … in both serous and endometrioid endometrial cancer patients. …

… is a useful platform to identify novel inhibitors. This platform led to the identification of dual
CDK2/9 inhibition as a promising therapeutic strategy to treat metastatic colorectal cancer. …

… Despite recent therapeutic achievements, thus, systemic treatment options remain … therapies
in the field of NETs, and also future perspectives of novel therapeutic drugs or strategies in …

… more and more attention, especially in the process of cancer. With its further studies, we
believe that PRAS40 can be used as a novel target for disease treatment and drug research. …

… , demanding novel treatment strategies such as immune checkpoint inhibition in tumors with
… of 10) but highly infrequent in neuroendocrine neoplasms from many other sites. The lack of …

… vasculature and tumor immunity, which play different roles in cancer progression. DLLs … as
anti-cancer therapeutics. In this review, we discuss the role of DLLs in cancer and summarize …