… therapeutic effect of these drugs is not as expected. Therefore, it is necessary to find a novel
therapy … insulin sensitivity, reduce weight and maintain the activity of pancreatic beta cells. …

… Hence, molecular markers have become a potent tool also in TC management to … as for
identification of novel therapeutic targets. In differentiated TC, molecular markers are mainly used …

… This review summarizes the current knowledge of structural features of LGALS3BP, its
pattern of expression in cancer and the potential role as novel therapeutic target in cancer. …

… evasion strategies of the tumor cells. This could be driven by both cellular and molecular …
as diagnostic and/or prognostic marker or as novel therapeutic target for both malignancies. …

… and a complex TME in prostate cancer suggests the need for identifying new … strategies
based on patient-specific molecular signatures. There is also a need to adjust strategies to …

… Therapeutic strategies targeting the tumor microenvironment. The TME is resided by diverse
… Multiple potential therapeutic strategies directly targeting critical TME processes have been …

… Nevertheless, even Rb-deficient LCNEC appear to have lower chemosensitivity than
conventional SCLC 102 , emphasizing the need for novel treatment approaches for these tumors. …

… Indeed, families with many members developing NPC have been studied, yet there are no
clear genetic markers that fully elucidate the seemingly strong predisposition for NPC in these …

… In a phase I study involving 10 patients with refractory solid tumors, one patient with a
duodenal neuroendocrine tumor showed prolonged stabilization of the disease for 24 weeks. …

… In addition to biomarkers, an exponential increase in the number of novel therapeutic UC
targets has been observed in the past decade, although it is interesting to note that their …