… that culminate in NLRP3 inflammasome complex assembly. A better understanding of the
molecular mechanisms underlying NLRP3 inflammasome activation will provide opportunities …

… activation and inactivation of NLRP3 inflammasome. This review summarizes current
understanding of the molecular basis of NLRP3 inflammasome activation … at NLRP3 …

… regulate NLRP3 expression to provide therapeutic insights for treating inflammasome related
… , positively regulates NLRP3 inflammasome activation through its phosphatase activity [89]. …

… the NLRP3 inflammasome. Firstly, the existing research mainly focuses on the molecular
mechanism of potassium efflux during ATP-induced NLRP3 inflammasome activation. The …

… and molecular mechanisms underlying the regulation of … NLRP3 inflammasome activation
by regulating NLRP3 … -mediated negative regulation of the NLRP3 inflammasome include the …

… In this review, we will explore the molecular processes underlying the activation of several …
steps in inflammasome activation. NLRP3 inflammasome activation involves TLR signalling to …

… modifications regulate the NLRP3 inflammasome at both the priming and activation steps. …
binding protein 1 regulates NLRP3 activation through RIPK1-RIPK3-caspase-8 signaling [ …

… implicate structure-derived mechanisms for the assembly and activation of the NLRP3 …
Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism. Nat. …

… inflammasome is the most extensively studied. In this review, … the mechanisms of NLRP3
inflammasome activation, how … Molecular Mechanisms of NLR Activation. Panel i describes …

… the updated molecular mechanisms implicated in the regulation of inflammasomes which …
To date, a two-step model has been well-established in NLRP3 inflammasome activation: a …