[PDF][PDF] Clinical implications of conventional cytogenetics, fluorescence in situ hybridization (FISH) and molecular testing in chronic myeloid leukaemia patients in the …

R Ankathil, SM Ismail, N Mohd Yunus, S Sulong… - Malays J …, 2020 - mjpath.org.my
… conventional haematologic remission and … fluorescence in situ hydridization method to
detect double BCR-ABL fusion and monitor response to therapy in chronic myeloid leukaemia. …

Treatment-free remission in patients with chronic myeloid leukaemia

DM Ross, TP Hughes - Nature reviews Clinical oncology, 2020 - nature.com
… (determined using fluorescence in situ hybridization or metaphase … Monitoring a TFR attempt
in a patient with an atypical … , an EUTOS long-term survival low-risk status was predictive …

Chronic myeloid leukemia: 2020 update on diagnosis, therapy and monitoring

E Jabbour, H Kantarjian - American journal of hematology, 2020 - Wiley Online Library
… patients with good performance status and organ functions, … Fluorescence in situ hybridization
studies may have a false … imatinib to achieve treatment-free remission (TFR) in patients …

Chronic myeloid leukemia: 2022 update on diagnosis, therapy, and monitoring

E Jabbour, H Kantarjian - American journal of hematology, 2022 - Wiley Online Library
… patients with good performance status and organ functions, … ABL1 abnormalities by
fluorescence in situ hybridization (FISH… the achievement of molecular remissions with a lower …

Digital PCR as a new method for minimal residual disease monitoring and treatment free remission management in chronic myeloid leukemia patients: is it reliable?

S Bernardi, M Malagola, M Farina, N Polverelli, F Re… - Hemato, 2022 - mdpi.com
… reliably measures the major breakpoint region and the presence of the fusion BCR-ABL1
gene and increases the sensitivity when compared to fluorescence in situ hybridization [58,59]. …

… Prognostication in Acute Myeloid Leukemia with CBFB-MYH11 Fusion Transcript: Focus on the Role of Molecular Measurable Residual Disease (MRD) Monitoring

A Talami, F Bettelli, V Pioli, D Giusti, A Gilioli… - Biomedicines, 2021 - mdpi.com
… to optimize post-remission monitoring and to define effective … as acute lymphoblastic or
chronic myeloid leukemia [64,65], … cytometry and fluorescence in situ hybridization examination …

Molecular Techniques in the Diagnosis and Monitoring of Acute and Chronic Leukaemias

HW Ip, WF Tang - Pathogenesis and Treatment of Leukemia, 2023 - Springer
… lymphoblastic leukaemias (ALL), chronic myeloid leukaemia (… karyotyping and fluorescence
in-situ hybridisation (FISH) for … of TKI therapy, termed treatment-free remission (TFR), in the …

Genomic mechanisms influencing outcome in chronic myeloid leukemia

A Fernandes, N Shanmuganathan, S Branford - Cancers, 2022 - mdpi.com
… In the 1990s, fluorescence in situ hybridization (FISH) techniques … The deletion status was
found to be an independent … -free remission due to lack of standardized monitoring; however, …

European LeukemiaNet laboratory recommendations for the diagnosis and management of chronic myeloid leukemia

NCP Cross, T Ernst, S Branford, JM Cayuela… - Leukemia, 2023 - nature.com
… of remission, and the possibility of attaining treatment-free … centres nowadays routinely use
fluorescence in situ hybridisation (FISH) to … call rate with appropriate control samples (which is …

… of minimal residual disease monitoring by real‐time quantitative polymerase chain reaction in core binding factor acute myeloid leukemia for transplantation outcomes

FF Yalniz, KP Patel, Q Bashir, D Marin, S Ahmed… - Cancer, 2020 - Wiley Online Library
… Cytogenetic analysis was performed by conventional fluorescence in situ hybridization (…
prognostic variables, including age, disease status (CR1 vs second complete remission [CR2]), …