Mouse models of atherosclerosis and their suitability for the study of myocardial infarction

P Golforoush, DM Yellon, SM Davidson - Basic research in cardiology, 2020 - Springer
… In this review, we examine the main mouse models of atherosclerosis currently available,
their method … The aim is to identify which, if any, mouse model of atherosclerosis is suitable for …

[HTML][HTML] Small rodent models of atherosclerosis

Y Zhao, H Qu, Y Wang, W Xiao, Y Zhang… - Biomedicine & …, 2020 - Elsevier
… and atherosclerosis lesions in apoE-/- mice, while the same anti-PCSK9 treatment could
reduce circulating TC and TG and attenuate atherosclerotic lesions in another mouse model, …

Animal models of atherosclerosis–supportive notes and tricks of the trade

A Gisterå, DFJ Ketelhuth, SG Malin… - Circulation …, 2022 - Am Heart Assoc
atherosclerotic plaques in the 1980s. The new immunologic tools together with genetically …
mouse models laid the foundation for deciphering the inflammatory etiology of atherosclerosis

Liraglutide treatment improves endothelial function in the Ldlr−/− mouse model of atherosclerosis and affects genes involved in vascular remodelling and …

KD Bjørnholm, GF Skovsted… - Basic & clinical …, 2021 - Wiley Online Library
mouse models of atherosclerosis, liraglutide has been demonstrated to result in a body-weight–independent
decrease in atherosclerotic … Moreover, liraglutide treatment of ApoE−/− mice

Role of reactive oxygen species in atherosclerosis: Lessons from murine genetic models

A Negre-Salvayre, P Guerby, S Gayral… - Free Radical Biology …, 2020 - Elsevier
… [51] using a model of apoe −/− mice transplanted with bone marrow from animals deficient …
reduced development of atherosclerosis in both models, when compared to control mice. The …

Atherosclerosis: Known and unknown

J Fan, T Watanabe - Pathology international, 2022 - Wiley Online Library
… The basic pathology of atherosclerosis is described below because this issue has seldom
… are using mouse models. The pathological descriptions of human atherosclerosis were first …

A novel mouse model of familial combined hyperlipidemia and atherosclerosis

M Chen, Y Xu, L Sun, Z Wang, PJ Little… - Acta Pharmacologica …, 2024 - nature.com
… In summary, this novel mouse model is of considerable clinical relevance for evaluation of
anti-atherosclerotic drugs by targeting both hypercholesterolemia and hypertriglyceridemia. …

Tissue factor in atherosclerosis and atherothrombosis

SP Grover, N Mackman - Atherosclerosis, 2020 - Elsevier
… was found to markedly reduce TF expression in atherosclerotic plaques [43]. Mouse
models of atherosclerosis have also been used extensively to study atherosclerosis [40]. …

Atherosclerosis: recent developments

JLM Björkegren, AJ Lusis - Cell, 2022 - cell.com
… associated with increased atherosclerosis. B cell autoimmunity can also contribute to
atherosclerosis; for example, some mouse models of lupus show increased atherosclerosis ( …

[HTML][HTML] Endothelial progenitor cell–derived exosomes ameliorate endothelial dysfunction in a mouse model of diabetes

S Bai, Q Yin, T Dong, F Dai, Y Qin, L Ye, J Du… - Biomedicine & …, 2020 - Elsevier
… Taken together, these results indicated that EPC-derived exosomes ameliorated atherosclerotic
endothelial dysfunction in a mouse model of atherosclerotic diabetes. Thus, the present …